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品質等級
化驗
99%
mp
126-128 °C (lit.)
官能基
ester
SMILES 字串
COC(=O)c1ccc2[nH]ccc2c1
InChI
1S/C10H9NO2/c1-13-10(12)8-2-3-9-7(6-8)4-5-11-9/h2-6,11H,1H3
InChI 密鑰
DRYBMFJLYYEOBZ-UHFFFAOYSA-N
一般說明
吲哚-5-甲酸甲酯(1H-吲哚-5-甲酸甲酯)是一种取代1H-吲哚,可以通过吲哚-5-羧酸的酯化反应进行制备。 已经评估了其作为靛类生成的底物的作用。
應用
吲哚-5-甲酸甲酯可用于制备:
- 二氢吲哚-5-甲酸甲酯
- 1H-吲哚-5-碳酰肼
- 1H-吲哚-3,5-二羧酸二甲酯
吲哚-5-甲酸甲酯可用作以下过程的反应物:
- 蛋白激酶抑制剂的生物合成
- 无金属的Friedel-Crafts烷基化反应
- 从Martin Sulfurane制备二苯基锍叶立德
- 交叉脱氢偶联反应
- 合成靛玉红衍生物
- 制备氨基吲哚乙酸盐
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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This report describes the synthesis, and in vitro and in vivo antimalarial evaluations of certain ester-modified neocryptolepine (5-methyl-5H-indolo[2,3-b]quinoline) derivatives. The modifications were carried out by introducing ester groups at the C2 and/or C9 position on the neocryptolepine core and the
Letters in Organic Chemistry, 7, 666-666 (2010)
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 21, 1407-1407 (2010)
Organic letters, 12(22), 5214-5217 (2010-10-23)
A novel cross dehydrogenative coupling (CDC) reaction of N,N-dimethylanilines with methyl ketones by cooperative copper and aminocatalysis has been developed, which leads to the formation of β-arylamino ketones in 42-73% yields. Moreover, the copper-catalyzed alkylation of free (NH) indoles with
A direct ylide transfer to carbonyl derivatives and heteroaromatic compounds.
Angewandte Chemie (International ed. in English), 49(47), 8979-8983 (2010-10-13)
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