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About This Item
经验公式（希尔记法）:
C12H10O5
CAS号:
分子量:
234.20
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗
97%
mp
193 °C (dec.) (lit.)
溶解度
DMF: soluble 50 mg/mL, clear, colorless to yellow
SMILES 字串
COc1ccc2C(CC(O)=O)=CC(=O)Oc2c1
InChI
1S/C12H10O5/c1-16-8-2-3-9-7(4-11(13)14)5-12(15)17-10(9)6-8/h2-3,5-6H,4H2,1H3,(H,13,14)
InChI 密鑰
ZEKAXIFHLIITGV-UHFFFAOYSA-N
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應用
已使用7-甲氧基香豆素-4-乙酸：
- 作为荧光探针，制备两个新型LysB29选择性标记的人胰岛素荧光衍生物
- 在细胞穿膜肽转运蛋白10（tp10）的制备中
- 作为肽的荧光标记
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
其他客户在看
Lindsay E Yandek et al.
Biophysical journal, 92(7), 2434-2444 (2007-01-16)
The mechanism of the interaction between the cell-penetrating peptide transportan 10 (tp10) and phospholipid membranes was investigated. Tp10 induces graded release of the contents of phospholipid vesicles. The kinetics of peptide association with vesicles and peptide-induced dye efflux from the
Stereospecific synthesis ofl-2-amino-3-(7-methoxy-4-coumaryl) propionic acid, an alternative to tryptophan in quenched fluorescent substrates for peptidases.
Knight CG.
Lett. Pept. Sci., 5(1), 1-4 (1998)
Alice Ciencialová et al.
Journal of peptide science : an official publication of the European Peptide Society, 10(7), 470-478 (2004-08-10)
The preparation and characterization of two novel LysB29 selectively labelled fluorescent derivatives of human insulin are described. Two probes were chosen: 4-chloro-7-nitrobenz-2-oxa-1,3-diazole (NBD) and 7-methoxycoumarin-4-acetic acid (MCA), which have a relatively small, compact structure and are able to react with
Tianshu Xiao et al.
Nature structural & molecular biology, 28(2), 202-209 (2021-01-13)
Effective intervention strategies are urgently needed to control the COVID-19 pandemic. Human angiotensin-converting enzyme 2 (ACE2) is a membrane-bound carboxypeptidase that forms a dimer and serves as the cellular receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ACE2 is
Ditlev Birch et al.
Biochimica et biophysica acta, 1859(12), 2483-2494 (2017-09-19)
Cell-penetrating peptides constitute efficient delivery vectors, and studies of their uptake and mechanism of translocation typically involve fluorophore-labeled conjugates. In the present study, the influence of a number of specific fluorophores on the physico-chemical properties and uptake-related characteristics of penetratin
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