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Merck

55155

Sigma-Aldrich

7-羟基香豆素-3-羧酸

suitable for fluorescence, ≥98.0% (capillary electrophoresis)

别名:

伞形酮-3-羧酸

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About This Item

经验公式(希尔记法):
C10H6O5
CAS号:
分子量:
206.15
Beilstein:
384141
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.32

品質等級

化驗

≥98.0% (capillary electrophoresis)

形狀

solid

pKa 

7.04

mp

261 °C (lit.)

溶解度

DMF: soluble
DMSO: soluble
alcohols: soluble

螢光

λex 342 nm; λem 447 nm (pH 4.0)
λex 386 nm; λem 448 nm in 0.1 M Tris pH 9.0

適合性

suitable for fluorescence

SMILES 字串

OC(=O)C1=Cc2ccc(O)cc2OC1=O

InChI

1S/C10H6O5/c11-6-2-1-5-3-7(9(12)13)10(14)15-8(5)4-6/h1-4,11H,(H,12,13)

InChI 密鑰

LKLWLDOUZJEHDY-UHFFFAOYSA-N

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應用

7-羟基香豆素-3-羧酸(7-OHCCA)可用作糖基转移酶试验的荧光底物。7-OHCCA可用作非肉桂酸类底物类似物,用于研究产酸克雷伯菌细胞中4-羟基肉桂酸脱羧酶 (4-HCD) 的诱导活性。它适合用作pH指示剂。

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

其他說明

固定在载体上,得到 pH 传感器

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Yuichiro Hori et al.
Journal of the American Chemical Society, 131(46), 16610-16611 (2009-11-03)
Protein labeling provides significant information about protein function. In this research, we developed a novel protein labeling technique by utilizing photoactive yellow protein (PYP). PYP is a small protein (14 kDa) derived from purple bacteria and binds to 7-hydroxycoumarin-3-carboxylic acid
Y Hashidoko et al.
Bioscience, biotechnology, and biochemistry, 65(12), 2604-2612 (2002-02-06)
The 4-hydroxycinnamate decarboxylase (4-HCD)-inducing activity of several substrate analogs toward Klebsiella oxytoca was investigated. Four E-cinnamate-class compounds, E-4-hydroxycinnamic acid (1), caffeic acid (2), ferulic acid (3) and E-2,4-dihydroxycinnamic acid (4), all of which were accepted as substrates, all of which
H. Offenbacher et al.
Sens. Actuators, 9, 73-73 (1986)
K Higai et al.
Biological & pharmaceutical bulletin, 22(4), 333-338 (1999-05-18)
We developed a novel fluorometric assay method for the measurement of glycosyltransferase activities using mono- and di-saccharides aminated and tagged with 7-hydroxycoumarin-3-carboxylic acid (coumarin) as substrates, N-acetylglucosamine (GlcNAc)-coumarin for beta1,4-galactosyltransferase from bovine milk and Gal beta1-4GlcNAc-coumarin for alpha2,3- and alpha2,6-sialyltransferases
Hang Wang et al.
European journal of mass spectrometry (Chichester, England), 22(1), 19-29 (2016-02-11)
Mass spectrometry has been applied to the targeted analysis of commonly used additives (such as Irganox 1010, Irganox 1076, Irgafos 168, etc.) in plastic materials, but a fast and straightforward method for the non-targeted identification and quantification of unusual or

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