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品質等級
化驗
≥99%
形狀
powder
mp
>300 °C (dec.) (lit.)
溶解度
DMF: soluble 5%, clear, colorless to yellow
官能基
chloro
SMILES 字串
Clc1ncnc2[nH]cnc12
InChI
1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
InChI 密鑰
ZKBQDFAWXLTYKS-UHFFFAOYSA-N
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一般說明
已研究 6-氯嘌呤与 3,4-二--O -乙酰基--D -木醛的酸催化反应。
應用
6-氯嘌呤在 DMSO 中通过各种取代卤代烷烃的烷基化反应制备 9-烷基嘌呤。也用于 6-琥珀氨基嘌呤的制备。
其他客户在看
Synthesis of Potential Anticancer Agents. XXVI. The Alkylation of 6-Chloropurine2.
Montgomery JA and Temple Jr C.
Journal of the American Chemical Society, 83(3), 630-635 (1961)
Synthesis of 6-succinoaminopurine.
C E CARTER
The Journal of biological chemistry, 223(1), 139-146 (1956-11-01)
Heterocyclic N-glycosides-V: Synthesis of unsaturated N-glycosides from 6-chloropurine and derivatives of d-xylal and l-arabinal. A conformational NMR study.
Fuertes M, et al.
Tetrahedron, 26(20), 4823-4837 (1970)
Masahiro Ikejiri et al.
Nucleic acids symposium series (2004), (51)(51), 439-440 (2007-11-22)
A series of nucleoside analogues whose 5'-hydroxyl groups are masked by various protective groups were synthesized and evaluated to develop novel anti- hepatitis C virus (HCV) agents. Among the several analogues that showed anti-HCV potency, a 5'-O-benzoyl-2'-deoxyribonucleoside analogue exhibited high
Dong-Chao Wang et al.
Organic & biomolecular chemistry, 9(22), 7663-7666 (2011-09-22)
An efficient method for the synthesis of 6-alkyl or 6-aryl purines (nucleosides) was developed via nickel-catalyzed Negishi cross-couplings of 6-chloropurines and organozinc halides. The ligand-free process gave good to excellent isolated yields at room temperature.
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