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Merck

136441

Sigma-Aldrich

丙二酸二甲酯

98%

别名:

Dimethyl propanedioate, Malonic acid dimethyl ester

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About This Item

线性分子式:
CH2(COOCH3)2
CAS号:
分子量:
132.11
Beilstein:
774261
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

>1 (vs air)

品質等級

化驗

98%

形狀

liquid

折射率

n20/D 1.413 (lit.)

bp

180-181 °C (lit.)

mp

−62 °C (lit.)

溶解度

alcohol: miscible
diethyl ether: miscible
oil: miscible
water: slightly soluble

密度

1.156 g/mL at 25 °C (lit.)

官能基

ester

SMILES 字串

COC(=O)CC(=O)OC

InChI

1S/C5H8O4/c1-8-4(6)3-5(7)9-2/h3H2,1-2H3

InChI 密鑰

BEPAFCGSDWSTEL-UHFFFAOYSA-N

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一般說明

丙二酸二甲酯与1,3-二苯基丙-2-烯基乙酸酯发生钯催化的对映选择性烯丙基取代反应,生成纯的非对映性噻吩基吡啶

應用

丙二酸二甲酯用于金催化的甘油、1,2-丙二醇和1,3-丙二醇的氧化酯化反应

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

185.0 °F - closed cup

閃點(°C)

85 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Chiral thienylpyridines as N-S ligands for asymmetric catalysis: Palladium-catalyzed allylic alkylation and copper-catalyzed cyclopropanation reactions.
Chelucci G, et al.
J. Mol. Catal. A: Chem., 197(1), 27-35 (2003)
Oxidation of glycerol and propanediols in methanol over heterogeneous gold catalysts.
Taarning E, et al.
Green Chemistry, 10(4), 408-414 (2008)
Jeroen S Dickschat et al.
Chembiochem : a European journal of chemical biology, 5(6), 778-787 (2004-06-03)
The volatiles emitted from cell cultures of myxobacterium Myxococcus xanthus were collected by use of a closed-loop stripping apparatus (CLSA) and analyzed by GC-MS. Two new natural products, (S)-9-methyldecan-3-ol ((S)-1) and 9-methyldecan-3-one (2), were identified and synthesized, together with other
B A McLaughlin et al.
Journal of neurochemistry, 70(6), 2406-2415 (1998-05-29)
Intrastriatal injections of the mitochondrial toxins malonate and 3-nitropropionic acid produce selective cell death similar to that seen in transient ischemia and Huntington's disease. The extent of cell death can be attenuated by pharmacological or surgical blockade of cortical glutamatergic
Violeta Iosub et al.
The Journal of organic chemistry, 75(5), 1612-1619 (2010-02-06)
A convenient and versatile enantioselective synthesis of biologically important alpha-quaternary amino acid derivatives was based on the sequential double alkylation or arylation of dimethyl malonate, followed by desymmetrization with porcine liver esterase (PLE) and Curtius rearrangement. The PLE-mediated hydrolysis of

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