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Merck

122696

Sigma-Aldrich

DL-1,2-异亚丙基甘油

≥97.0%

别名:

(±)-2,2-二甲基-1,3-二氧戊环-4-甲醇, (±)-2,2-二甲基-4-羟甲基-1,3-二氧戊环, 1,2-Isopropylidene-rac-glycerol, 丙酮缩甘油

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About This Item

经验公式(希尔记法):
C6H12O3
CAS号:
分子量:
132.16
Beilstein:
104465
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥97.0%

形狀

liquid

折射率

n20/D 1.434 (lit.)

bp

188-189 °C (lit.)

溶解度

H2O: miscible
alcohol: miscible
diethyl ether: miscible
oil: miscible
petroleum ether: miscible

密度

1.063 g/mL at 25 °C (lit.)

官能基

ether

SMILES 字串

CC1(C)OCC(CO)O1

InChI

1S/C6H12O3/c1-6(2)8-4-5(3-7)9-6/h5,7H,3-4H2,1-2H3

InChI 密鑰

RNVYQYLELCKWAN-UHFFFAOYSA-N

一般說明

DL-1,2-异亚丙基甘油在磷钨酸催化下发生有效的异亚丙基化脱保护反应

應用

以 DL-1,2-异亚丙基甘油为起始原料合成了郁金香酯衍生物

法律資訊

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Repr. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

194.0 °F - closed cup

閃點(°C)

90 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Alvise Perosa et al.
Molecules (Basel, Switzerland), 21(2), 170-170 (2016-02-04)
The caprylic, lauric, palmitic and stearic esters of solketal and glycerol formal were synthesized with high selectivity and in good yields by a solvent-free acid catalyzed procedure. No acetal hydrolysis was observed, notwithstanding the acidic reaction conditions.
Useful methods for the synthesis of isopropylidenes and their chemoselective cleavage.
Vanlaldinpuia K and Bez G.
Tetrahedron Letters, 52(29), 3759-3764 (2011)
Thomas Mendgen et al.
Bioorganic & medicinal chemistry letters, 20(19), 5757-5762 (2010-08-24)
The enzyme MurA performs an essential step in peptidoglycan biosynthesis and is therefore a target for the discovery of novel antibacterial compounds. We report here the inhibition of MurA by natural products from tulips (tulipalines and tuliposides), and the structure-activity
Renjie Liu et al.
Bioconjugate chemistry, 28(7), 1955-1964 (2017-06-22)
Electrospun biodegradable membranes have attracted great attention for a range of tissue engineering applications. Among them, poly(ε-caprolactone) (PCL) is one of the most widely used polymers, owing to its well-controlled biocompatibility and biodegradability. However, PCL also has a number of
Aldo Jongejan et al.
Biochimica et biophysica acta, 1647(1-2), 297-302 (2003-04-11)
Isotopic substitution provides an effective tool to probe the mechanism of enzyme-catalyzed reactions. To our knowledge, kinetic isotope effects on the enantioselectivity of enzymes have not been reported. We investigated the effect of deuterium substitution on the enantiomeric ratio, E

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