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Steviol

analytical standard

Synonyme(s) :

(4α)-13-Hydroxykaur-16-en-18-oic acid, ent-13-Hydroxykauran-16-en-19-oic acid, NSC 226902

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About This Item

Formule empirique (notation de Hill):
C20H30O3
Numéro CAS:
471-80-7
Poids moléculaire :
318.45
Numéro MDL:
MFCD00210558
Code UNSPSC :
85151701
ID de substance PubChem :
329751845
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Pureté

≥98.0% (HPLC)

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Impuretés

≤5.0% water (Karl Fischer)

Application(s)

cleaning products
cosmetics
food and beverages
personal care

Format

neat

Chaîne SMILES 

C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O

InChI

1S/C20H30O3/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19/h14-15,23H,1,4-12H2,2-3H3,(H,21,22)/t14-,15-,17+,18+,19+,20-/m0/s1

Clé InChI

QFVOYBUQQBFCRH-VQSWZGCSSA-N

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Description générale

Steviol, a diterpenoiic carboxylic alcohol is an aglycone of sweet glycosides which is accumulated in Stevia rebaudiana. ent-kaurenoic acident-KA undergoes hydroxylation reaction in presence of molecular oxygen and NADPH, to yield steviol.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Steviol may have been used as reference standard to compare retention time and UV spectra in HPLC analysis for the quantification of steviol in Aconitum heterophyllum plant extract.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
BCCH9042
BCCH0745
BCCG4392
BCCG1112
BCCF4963

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Sigma-Aldrich

SMB00144

Labdanolic acid

Stevioside phyproof® Reference Substance

PHL89800

Stevioside

Rebaudioside M ≥95.0% (HPLC)

Sigma-Aldrich

74632

Rebaudioside M

H Shibata et al.
Plant physiology, 95(1), 152-156 (1991-01-01)
To evaluate and characterize stevioside biosynthetic pathway in Stevia rebaudiana Bertoni cv Houten, two enzyme fractions that catalyze glucosylation of steviol (ent-13-hydroxy kaur-16-en-19-oic acid) and steviol-glucosides (steviol-13-O-glucopyranoside, steviolbioside and stevioside), utilizing UDP-glucose as the glucose donor, were prepared from the
Molecular dissection of pathway components unravel atisine biosynthesis in a non-toxic Aconitum species, A. heterophyllum Wall.
Kumar, Varun, et al.
3 Biotech, 6.1, 1-10 (2016)
Claudio Gardana et al.
Journal of chromatography. A, 1217(9), 1463-1470 (2010-01-28)
Stevia rebaudiana leaves contain non-cariogenic and non-caloric sweeteners (steviol-glycosides) whose consumption could exert beneficial effects on human health. Steviol-glycosides are considered safe; nonetheless, studies on animals highlighted adverse effects attributed to the aglycone steviol. The aim of the present study
Benno F Zimmermann
Rapid communications in mass spectrometry : RCM, 25(11), 1575-1582 (2011-05-20)
Stevia rebaudiana contains several steviol glycosides that have a sweet flavor. They are up to 450 times sweeter than sucrose, but some have an undesirable aftertaste. Up to 2010, ten different steviol glycosides have been described from the leaves or
D J Brusick
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46 Suppl 7, S83-S91 (2008-06-17)
Extracts of the leaves of the stevia plant (Stevia rebaudiana Bertoni) are used to sweeten food and beverages in South America, Japan and China. The components responsible for the sweet properties of the plant are glycosides of steviol, primary stevioside
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Articles

Separation of Steviol Glycosides by HPTLC: Introducing a New Stevia Extract Reference Material

HPTLC is an efficient method to determine Steviol Glycosides content in Stevia using our HPTLC plates and reference materials, including a new introduced Stevia extract reference material.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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