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1462006

USP

Nicotinamide

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Nicotinamide, Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

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About This Item

Fórmula empírica (notación de Hill):
C6H6N2O
Número de CAS:
98-92-0
Peso molecular:
122.12
Beilstein:
383619
Número MDL:
MFCD00006395
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329750553
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

nicotinamide

fabricante / nombre comercial

USP

mp

128-131 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

Clave InChI

DFPAKSUCGFBDDF-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Niacinamide USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, Niacin standard solution, standard niacinamide stock solution, and sample solution for assay, performance, and strength analysis according to the given below monographs and general chapters of United States Pharmacopeia (USP):
  • Niacinamide
  • Niacinamide Tablets
  • Niacinamide Injection
  • 〈441〉 Niacin or Niacinamide Assay

Acciones bioquímicas o fisiológicas

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

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Descripción
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Nicotinamide, European Pharmacopoeia (EP) Reference Standard

E2400000

Ethylnicotinamide, European Pharmacopoeia (EP) Reference Standard

BP460

Nicotinamide, British Pharmacopoeia (BP) Reference Standard

BP1104

N-(2-Hydroxyethyl)isonicotinamide nitric ester, British Pharmacopoeia (BP) Reference Standard

PHR2089

Nicotinamide Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2090

Nicotinamide Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2088

Nicotinamide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2087

Nicotinamide Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H319

Clasificaciones de peligro

Eye Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

302.0 °F - closed cup

Punto de inflamabilidad (°C)

150 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number

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United States Pharmacopeia, 46(5) (2023)
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European journal of cancer (Oxford, England : 1990), 50(6), 1112-1119 (2014-01-16)
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Marcia S Brose et al.
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Nicotinamide adenine dinucleotide (NAD+) biosynthesis from nicotinamide is used by mammalian cells to replenish their NAD+ stores and to avoid unwanted nicotinamide accumulation. Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the key enzyme in this biosynthetic pathway, almost invariably leads to
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