N0600000

Nicotinamide

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B₃, Vitamin PP
• Fórmula empírica (notación de Hill): C₆H₆N₂O
• Número de CAS: 98-92-0
• Peso molecular: 122.12
• Beilstein: 383619
• Número MDL: MFCD00006395
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329818447
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• grado: pharmaceutical primary standard
• familia API: nicotinamide
• formulario: solid
• fabricante / nombre comercial: EDQM
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: 128-131 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: NC(=O)c1cccnc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• Clave InChI: DFPAKSUCGFBDDF-UHFFFAOYSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B₃). It is available in food products and is utilized for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also known for its anti-inflammatory activity.

Aplicación

Nicotinamide can be used as an EP reference standard for the quantification of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.

Acciones bioquímicas o fisiológicas

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H319
• Consejos de prudencia: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Clasificaciones de peligro: Eye Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 302.0 °F - closed cup
• Punto de inflamabilidad (°C): 150 °C - closed cup