SMB00288

Peptidoglycan from Bacillus subtilis

≤1.00 EU/mg Endotoxin

• Sinónimos: PGN
• Número MDL: MFCD00212486
• Código UNSPSC: 12352201
• NACRES: NA.25

Propiedades

• origen biológico: Bacillus subtilis
• Nivel de calidad: 200
• Formulario: lyophilized powder
• impurezas: ≤1.00 EU/mg Endotoxin
• solubilidad: water: 9.80-10.20 mg/mL, hazy to turbid
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Peptidoglycan.is a biopolymer that is a major component of the cell walls of Gram-positive bacteria. Peptidoglycan consists of a carbohydrate backbone of alternating units of N-acetyl glucosamine and N-acetyl muramic acid and is modified with both D- and L-amino acids. N-Acetyl muramic acid residues are cross-linked with oligopeptides. The terminal peptide is D-alanine although other amino acids are present as D-isomers.

Aplicación

Peptidoglycan may be used for the activity estimation of lytic enzymes (e.g. lyticase). It is recommended to use a peptidoglycan concentration of 0.15-3 μg/ml in water or buffer and measuring at 450 nm. The peptidoglycan is not soluble but produces a suspension in water.
Peptidoglycan activates the Toll-like receptor 2 (TLR2), present in mammalian cells for the stimulation of lymphocytes. It may also function as an antagonist of Poly (I:C).

Otras notas

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable