A9519

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate

≥98% (TLC), suitable for ligand binding assays

• Sinónimos: Adjuvant Peptide, Muramyl dipeptide
• Fórmula empírica (notación de Hill): C₁₉H₃₂N₄O₁₁ · xH₂O
• Número de CAS: 53678-77-6
• Peso molecular: 492.48 (anhydrous basis)
• Beilstein: 4220745
• Número CE: 258-696-9
• Número MDL: MFCD00077638
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 24891464
• NACRES: NA.26

Propiedades

• Nombre del producto: N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate, ≥98% (TLC)
• Nivel de calidad: 200
• Ensayo: ≥98% (TLC)
• Formulario: powder
• técnicas: ligand binding assay: suitable
• color: white
• aplicaciones: cell analysis
• temp. de almacenamiento: −20°C
• cadena SMILES: C[C@H](NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(C)=O)C(=O)N[C@H](CCC(O)=O)C(N)=O
• InChI: 1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19?/m0/s1
• Clave InChI: BSOQXXWZTUDTEL-QAQREVAFSA-N

Descripción

Amino Acid Sequence

MurNAc-Ala-Agn

Aplicación

N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.

Acciones bioquímicas o fisiológicas

Enhances antigenicity of weak antigens, increasing antibody titer.

Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.

N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP, muramyl dipeptide), a neurotrophic and immunomodulatory factor related to bacterial peptidoglycans, is used as an immune modulation factor that enhances immune response and to study neural development.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)