N8159
Albumin, Nitrated from bovine serum
lyophilized powder
Sinónimos:
Nitrated BSA
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About This Item
Productos recomendados
origen biológico
bovine
Nivel de calidad
Formulario
lyophilized powder
técnicas
immunoblotting: suitable
Nº de acceso UniProt
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
bovine ... ALB(280717)
Descripción general
Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.
Aplicación
Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).
Acciones bioquímicas o fisiológicas
Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.
Forma física
Lyophilized from 0.01 M phosphate buffered saline, pH 7.4
Nota de preparación
Bovine serum albumin (BSA) nitrated with peroxynitrite.
Nota de análisis
Does not contain sodium azide
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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