D8156
Monoclonal Anti-Digoxin antibody produced in mouse
clone DI-22, ascites fluid
Sinónimos:
Monoclonal Anti-Digoxin
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.43
Productos recomendados
origen biológico
mouse
conjugado
unconjugated
forma del anticuerpo
ascites fluid
tipo de anticuerpo
primary antibodies
clon
DI-22, monoclonal
contiene
15 mM sodium azide
técnicas
dot blot: suitable
flow cytometry: suitable
indirect ELISA: 1:10,000 using digoxin-BSA
indirect ELISA: 1:2,500 using digoxigenin-transferrin
isotipo
IgG1
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
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Descripción general
Monoclonal Anti-Digoxin (mouse IgG1 isotype) is derived from the hybridoma DI-22 produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with digoxin- keyhole limpet hemocyanin (KLH). Digoxin is obatained from the leaves of the Digitalis lanata, a foxglove plant. The digoxin molecule is made up of a sugar and a cardenolide. It has a molecular weight is 780.95 Da. It is a odorless white crystal, which is soluble in alcohol and freely soluble in pyridine. It is expressed in the duodenum, kidneys, liver and the blood-brain barrier.
Especificidad
Antibody is specific for digoxin and shows a high affinity for digoxigenin.
Monoclonal Anti-Digoxin antibody is specific for digoxin and digoxin-labeled compounds, and shows strong cross-reactivity with digoxigenin.
Inmunógeno
Digoxin-KLH.
Aplicación
Monoclonal Anti-Digoxin antibody produced in mouse has been used in:
- enzyme-linked immunosorbent assay (ELISA)
- dot blot
- flow cytometry
- fluorescence in situ hybridization (FISH)
- DNA hybridization
- in-situ hybridization (ISH)
- immunodetection of the probe and chromosome X
Acciones bioquímicas o fisiológicas
Digoxin is a phytoestrogen that binds estrogen receptors and produces inotropic effects in cardiac muscle. Studies show that digoxin decreases the risk of breast and uterus cancers that are estrogen sensitive.
Digoxin is a substrate for P-glycoprotein (P-gp), a membrane efflux transporter. This antibody may be used to detect digoxin-labeled compounds such as oligonucleotides, antibodies or peptides.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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