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Merck

B1215000

2,6-Di-tert-butyl-4-methylphenol

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

2,6-Di-tert-butyl-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC

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About This Item

Fórmula lineal:
[(CH3)3C]2C6H2(CH3)OH
Número de CAS:
Peso molecular:
220.35
Beilstein:
1911640
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

densidad de vapor

7.6 (vs air)

presión de vapor

<0.01 mmHg ( 20 °C)

temp. de autoignición

878 °F

fabricante / nombre comercial

EDQM

bp

265 °C (lit.)

mp

69-73 °C (lit.)

aplicaciones

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

Clave InChI

NLZUEZXRPGMBCV-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación


  • Multicomponent analysis of fat- and water-soluble vitamins and auxiliary substances in multivitamin preparations by qNMR.: This study utilizes Butylhydroxytoluene (BHT) as an auxiliary substance for its antioxidant properties in multivitamin preparations. The research demonstrates the effectiveness of BHT in maintaining the oxidative stability of vitamins, ensuring their longevity and efficacy in pharmaceutical applications (Eiff et al., 2015).

  • Investigation of the stabilizing effects of antioxidants and benzophenone-3 on desonide photostability.: The study explores the use of BHT as an antioxidant to enhance the photostability of desonide. Findings indicate that BHT significantly improves the stability of the compound under light exposure, making it a valuable preservative in pharmaceutical and biotechnological formulations (Rosa et al., 2014).


  • Understanding the molecular aspects of tetrahydrocannabinol and cannabidiol as antioxidants.: This research highlights BHT′s role as a comparative antioxidant in studying the properties of cannabinoids. BHT′s well-documented antioxidant mechanisms provide a benchmark for evaluating the efficacy of other compounds in oxidative stress research (Borges et al., 2013).


  • Kinetic study of the quenching reaction of singlet oxygen by common synthetic antioxidants.: The kinetic analysis of BHT′s ability to quench singlet oxygen demonstrates its superior antioxidant capabilities compared to other synthetic antioxidants. This property is crucial for developing pharmaceutical formulations that require high oxidative stability (Kim et al., 2009).



Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Environment

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

260.6 °F - open cup

Punto de inflamabilidad (°C)

127 °C - open cup


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Urszula Kołodziej et al.
Archives of oral biology, 84, 6-12 (2017-09-20)
Chronic high protein intake leads to an increase in reactive oxygen species (ROS) generation. However, there is no data on the impact of high-protein diet on the antioxidant barrier, oxidative stress and secretory function in the salivary glands of healthy
Priscila Sutto-Ortiz et al.
PeerJ, 5, e3524-e3524 (2017-07-12)
Novel microbial phospholipases A (PLAs) can be found in actinomycetes which have been poorly explored as producers of this activity. To investigate microbial PLA production, efficient methods are necessary such as high-throughput screening (HTS) assays for direct search of PLAs in
Ana Claudia Hertel Pereira et al.
Pharmaceutical biology, 55(1), 472-480 (2016-12-13)
The resin from the trunk wood of Virola oleifera (Schott) A. C. Smith (Myristicaceae) is used in folk medicine to hasten wound repair and to treat pain and inflammatory conditions, and our previous report indicated the anti-oxidative properties in other
Mateusz Maciejczyk et al.
Nutrients, 10(10) (2018-10-20)
A high-sucrose diet (HSD) is widely known for its cariogenic effects and promotion of obesity, insulin resistance, type 2 diabetes, and cancer. However, the impact of the HSD diet on the salivary gland function as well as the level of
Hanene Cherchar et al.
Planta medica, 85(11-12), 1008-1015 (2019-07-03)
One new natural monoterpene, 5-O-β-d-glucopyranosyl-2-hydroxy-p-cymene (1: ), and 11 known compounds were isolated through a biologically oriented approach from the aerial parts of Phagnalon sordidum L. The most active extract and fractions were selected using 3 complementary antioxidant activity assays.

Protocolos

HPLC Analysis of Phenolic Antioxidants on Ascentis® Express C18 2.7 μm

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