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Merck

W218405

Sigma-Aldrich

2,6-Di-tert-butyl-4-methylphenol

≥99%, FCC, FG

Sinónimos:

2,6-Di-tert-butyl-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC

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About This Item

Fórmula lineal:
[(CH3)3C]2C6H2(CH3)OH
Número de CAS:
Peso molecular:
220.35
Número de FEMA:
2184
Beilstein:
1911640
Número CE:
Número MDL:
Código UNSPSC:
12164502
ID de la sustancia en PubChem:
Número E:
E 321
NACRES:
NA.21
Organoléptico:
camphoraceous
grado:
FG
Fragrance grade
Kosher
origen biológico:
synthetic
Agency:
follows IFRA guidelines
alérgeno alimentario:
no known allergens

origen biológico

synthetic

Nivel de calidad

grado

FG
Fragrance grade
Kosher

Agency

follows IFRA guidelines

cumplimiento norm.

EU Regulation 1223/2009
EU Regulation 1333/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.115

densidad de vapor

7.6 (vs air)

presión de vapor

<0.01 mmHg ( 20 °C)

Ensayo

≥99%

Formulario

powder or crystals

temp. de autoignición

878 °F

bp

265 °C (lit.)

mp

69-73 °C (lit.)

aplicaciones

flavors and fragrances

Documentación

see Safety & Documentation for available documents

alérgeno alimentario

no known allergens

alérgeno de la fragancia

no known allergens

Organoléptico

camphoraceous

cadena SMILES

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

Clave InChI

NLZUEZXRPGMBCV-UHFFFAOYSA-N

Información sobre el gen

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Descripción general

Butylated hydroxytoluene is a synthetic phenolic compound mainly used as an antioxidant and preservative in the food industry. It is used to prevent the lipid oxidation in oils and fat-containing foods.

Aplicación


  • Role of odorant binding protein C12 in the response of Tribolium castaneum to chemical agents.: This article explores the impact of BHT on insect biochemistry, specifically how it affects the binding affinity of odorant-binding proteins in pests, providing insights into developing more effective pest control strategies (Wang et al., 2024).

  • A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3-nitropropionic acid in in vitro and in vivo models.: Research includes BHT as a comparative standard in studying neuroprotective agents, underscoring its role in biochemical pathways related to oxidative stress and neuroprotection (Campos et al., 2024).

  • Simultaneous Determination of Fipronil, Permethrin and their Key Related Substances in a Topical Drug Product by a Single Stability Indicating High Performance Liquid Chromatography Method.: BHT is used as an internal standard to assess the stability and integrity of pharmaceutical products, demonstrating its utility in pharmaceutical analysis (Rathnasekara et al., 2024).

  • Pyrano[2,3-c]pyrazole fused spirooxindole-linked 1,2,3-triazoles as antioxidant agents: Exploring their utility in the development of antidiabetic drugs via inhibition of a-amylase and DPP4 activity.: This study utilizes BHT as a reference antioxidant to compare the efficacy of newly synthesized compounds, providing a benchmark in antioxidant research for diabetes treatment (Chahal et al., 2024).

Pictogramas

Environment

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

260.6 °F - open cup

Punto de inflamabilidad (°C)

127 °C - open cup

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves


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Visite la Librería de documentos

Burdock GA
Encyclopedia of Food and Color Additives, 1, 327-330 (1997)
Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives
Williams GM, et al.
Food And Chemical Toxicology, 37(9), 1027-1038 (1999)
Safety aspects of food preservatives
Parke DV & Lewis DFV
Food Additives and Contaminants, 9(5), 561-577 (1992)
Silvia Carvajal et al.
Scientific reports, 9(1), 12848-12848 (2019-09-08)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide, ranging from steatosis to non-alcoholic steatohepatitis (NASH). Recently, cerium oxide nanoparticles (CeO2NPs) have emerged as a new antioxidant agent with hepatoprotective properties in experimental liver
A M Vijesh et al.
European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)
In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized

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