81242
Poli(etilenglicol)
tested according to Ph. Eur., 4,000
Sinónimos:
PEG
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About This Item
Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
Número MDL:
Código UNSPSC:
12352104
ID de la sustancia en PubChem:
NACRES:
NA.21
Productos recomendados
Agency
tested according to Ph. Eur.
Nivel de calidad
formulario
solid
mol peso
3500-4500
aplicaciones
pharmaceutical (small molecule)
cadena SMILES
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
Clave InChI
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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Descripción general
Poly(ethylene glycol) (PEG) is a non-toxic water-soluble polymer. PEG term is used for the polymer chains with molecular weights below 20 000, while poly(ethylene oxide) (PEO) refers to the higher molecular weight polymers. PEG has various biomedical applications. It forms complexes with α-cyclodextrins. Engineering of PEG hydrogel particles by mesoporous silica (MS) templating method has been reported.
Aplicación
Poly(ethylene glycol) may be used in the following studies:
- For the modification of proteins to form the conjugates having increased circulating life and reduced immunogenicity and antigenicity.
- Preparation of hydrogels useful for the diffusion controlled delivery of proteins.
- Preparation of poly(ethylene glycol) dimethacrylate (PEGDM).
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Los clientes también vieron
The clinical efficacy of poly (ethylene glycol)-modified proteins.
Fuertges F and Abuchowski A.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 11(1), 139-148 (1990)
N A Peppas et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(1-2), 81-87 (1999-10-16)
The use of hydrogels as carriers for protein delivery has been a subject of significant recent research. In our recent work, we have shown that diffusion controlled delivery of proteins from hydrogels containing poly(ethylene glycol) (PEG) can be possible and
Stephanie J Bryant et al.
Annals of biomedical engineering, 32(3), 407-417 (2004-04-21)
In approaches to tissue engineer articular cartilage, an important consideration for in situ forming cell carriers is the impact of mechanical loading on the cell composite structure and function. Photopolymerized hydrogel scaffolds based on poly(ethylene glycol) (PEG) may be synthesized
Complex formation between poly (ethylene glycol) and α-cyclodextrin.
Harada A and Kamachi M.
Macromolecules, 23(10), 2821-2823 (1990)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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