65943

N-Methyl-bis(trifluoroacetamide)

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• Sinónimos: MBTFA
• Fórmula lineal: CF₃CON(CH₃)COCF₃
• Número de CAS: 685-27-8
• Peso molecular: 223.07
• Beilstein: 1878402
• Número CE: 211-680-5
• Número MDL: MFCD00000412
• Código UNSPSC: 12000000
• ID de la sustancia en PubChem: 329760134
• NACRES: NA.22

Propiedades

• grado: derivatization grade ((GC derivatization)); for GC derivatization
• Nivel de calidad: 100
• Ensayo: ≥99.0% (GC)
• calidad: LiChropur^™
• idoneidad de la reacción: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Silylations
• técnicas: gas chromatography (GC): suitable
• índice de refracción: n20/D 1.346 (lit.); n20/D 1.346
• bp: 121-122 °C (lit.)
• densidad: 1.547 g/mL at 25 °C
• cadena SMILES: CN(C(=O)C(F)(F)F)C(=O)C(F)(F)F
• InChI: 1S/C5H3F6NO2/c1-12(2(13)4(6,7)8)3(14)5(9,10)11/h1H3
• Clave InChI: AWGBWLXGUPTXHF-UHFFFAOYSA-N

Descripción

Descripción general

N-Methyl-bis(trifluoroacetamide) is a common reagent used in the alkylation process, which targets highly polar, multi-functional compounds such as carbohydrates and amino acids.

Aplicación

N-Methyl-bis(trifluoroacetamide) may be used as an on-column derivatization agent for the determination of amphetamine-type stimulants in biological samples, and ketamine, norketamine, dehydronorketamine in urine samples using gas chromatography coupled to mass spectrometry technique.
It is a derivatization agent in GC-MS technique used as an alternative to trifluoroacetyl anhydride (TFAA) for trifluoroacylating primary and secondary amines, and the hydroxyl group under mild non-acidic conditions.
Reagent for introducing trifluoroacetyl group. Suitable for the derivatization of alcohols, amines, amino acids, carbohydrates(mono-,di-,tri- and tetrasaccharides, carboxylic acids, hydroxyamines, 3-hydroxy-1-nitrosopyrrolidine, indolalkylamine, phenolalkylamines, pyridoxal (and other B₆ vitamers), and thiols.

Reagent for introducing trifluoroacetyl group.

Otras notas

Reagent for trifluoroacetyl, N-trimethylsilyl-N-tifluoroacetyl and trimethylsilyl.

Reagent for trifluoroacetylations under mild conditions

Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H226,H314
• Consejos de prudencia: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Clasificaciones de peligro: Flam. Liq. 3 - Skin Corr. 1B
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 113.0 °F - closed cup
• Punto de inflamabilidad (°C): 45 °C - closed cup
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter