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NB20

Sigma-Aldrich

Anti-AnkyrinG Mouse mAb (463)

liquid, ≥95% (SDS-PAGE), clone 463

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100

forma del anticuerpo

purified antibody

tipo de anticuerpo

primary antibodies

clon

463, monoclonal

Análisis

≥95% (SDS-PAGE)

formulario

liquid

contiene

≤0.1% sodium azide as preservative

reactividad de especies

rat, mouse, human, canine

fabricante / nombre comercial

Calbiochem®

condiciones de almacenamiento

do not freeze

isotipo

IgG1

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ANK3(288)

Descripción general

Anti-Ankyrin G, mouse monoclonal, clone 463, recognizes the ~190 kDa ankyrin G protein in brain extracts. It is validated for Western blotting, immunofluorescence, and frozen sections.
Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with P3X63/Ag 8.653 mouse myeloma cells. Recognizes the ~190 kDa isoform of AnkyrinG.
Recognizes the ~190 kDa ankyrinG protein in brain extracts. Reacts with all spliced forms of ankyrinG.
  • Antibody Target Gene Symbol: ANK3
  • Target Synonym: 2900054D09RIK, AI314020, AnkG, Ankyrin-3, ANKYRIN-G, FLJ45464, MGC14049
  • Entrez Gene Name: ankyrin 3, node of Ranvier (ankyrin G)
  • Hu Entrez ID: 288 (Related Antibodies: AP1034, PC523, PC522, AP1057)
  • Mu Entrez ID: 11735
  • Rat Entrez ID: 361833

    • Inmunógeno

    Human
    a synthetic peptide corresponding to amino acids from the spectrin-binding domain of human ankyrinG

    Aplicación


    Frozen Sections (1-2 g/ml)
    Immunoblotting (2-5 g/ml)
    Immunofluorescence (1-2 g/ml)

    Envase

    Please refer to vial label for lot-specific concentration.

    Advertencia

    Toxicity: Standard Handling (A)

    Forma física

    In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.

    Nota de análisis

    Positive Control
    Mouse or rat brain extract or unmyelinated axons

    Otras notas

    AnkyrinG is a good immunohistochemical marker for axon initial segments, nodes of Ranvier, and epithelial cell-cell contact sites. Antibody should be titrated for optimal results in individual systems.
    Davis, J.Q., et al. 1995. Mol. Biol. Cell6, 177a, supplement.
    Kunimoto, M., et al. 1995. FEBS Lett.357, 217.
    Lambert, S., et al. 1995. Mol. Biol. Cell6, 98a supplement.
    Bennett, V. and Gilligan, D.M. 1993. Ann. Rev. Cell Biol.9, 27.
    Kunimoto, M., et al. 1991. J. Cell Biol.115, 1319.
    Otto, E., et al. 1991. J. Cell Biol.114, 241.
    Davis, J., and Bennett, V. 1984. J. Biol. Chem.259, 13550.

    Información legal

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    Código de clase de almacenamiento

    10 - Combustible liquids

    Clase de riesgo para el agua (WGK)

    nwg

    Punto de inflamabilidad (°F)

    Not applicable

    Punto de inflamabilidad (°C)

    Not applicable

    Certificados de análisis (COA)

    Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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