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Merck
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Key Documents

16-189

Sigma-Aldrich

Anti-phospho-Histone H3 (Ser10) Antibody, biotin conjugate

Upstate®, from rabbit

Sinónimos:

H3 histone, family 3A, H3S10P, Histone H3 (phospho S10), H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B)

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

biotin conjugate

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

human

fabricante / nombre comercial

Upstate®

técnicas

immunocytochemistry: suitable
western blot: suitable

isotipo

IgG

Nº de acceso NCBI

NM_003493.2

Nº de acceso UniProt

Q16695

Condiciones de envío

wet ice

modificación del objetivo postraduccional

phosphorylation (pSer10)

Información sobre el gen

human ... HIST1H3F(8968)

Inmunógeno

KLH-conjugated peptide (ARK[pS]TGGKAPRKQL- C) corresponding to amino acids 7-20 of human histone H3.

Aplicación

Anti-phospho-Histone H3 (Ser10) Antibody, biotin conjugate is a Rabbit Polyclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,is biotinylated, published in peer reviewed journals and has been validated in WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Calidad

routinely evaluated in immunocytochemistry by immunostaining chromatin in HeLa cells undergoing mitosis

Forma física

PBS, pH 7.4, with 0.05% sodium azide.
Protein A purified

Almacenamiento y estabilidad

6 months at 4°C

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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An-Sofie Stevens et al.
Scientific reports, 7, 45616-45616 (2017-05-04)
One of the major challenges in the development of alternative carcinogenicity assays is the prediction of non-genotoxic carcinogens. The variety of non-genotoxic cancer pathways complicates the search for reliable parameters expressing their carcinogenicity. As non-genotoxic and genotoxic carcinogens have different
An-Sofie Stevens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 162(1), 251-263 (2017-11-18)
Aiming to in vivo characterize the responses of pluripotent stem cells and regenerative tissues to carcinogenic stress, we employed the highly regenerative organism Schmidtea mediterranea. Its broad regenerative capacities are attributable to a large pool of pluripotent stem cells, which
Jason D Gray et al.
Human molecular genetics, 22(21), 4267-4281 (2013-06-19)
Low-density lipoprotein receptor related protein 6 (Lrp6) mutational effects on neurulation were examined using gain (Crooked tail, Lrp6(Cd)) and loss (Lrp6(-)) of function mouse lines. Two features often associated with canonical Wnt signaling, dorsal-ventral patterning and proliferation, were no different
An-Sofie Stevens et al.
Journal of applied toxicology : JAT, 35(3), 319-326 (2014-06-27)
To investigate hydrophobic test compounds in toxicological studies, solvents like dimethylsulfoxide (DMSO) are inevitable. However, using these solvents, the interpretation of test compound-induced responses can be biased. DMSO concentration guidelines are available, but are mostly based on acute exposures involving
Jason D Gray et al.
Human molecular genetics, 19(23), 4560-4572 (2010-09-17)
Crooked tail (Cd) mice bear a gain-of-function mutation in Lrp6, a co-receptor for canonical WNT signaling, and are a model of neural tube defects (NTDs), preventable with dietary folic acid (FA) supplementation. Whether the FA response reflects a direct influence
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