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ANK3

ankyrin 3, node of Ranvier (ankyrin G)

Synonyms:
ANKYRIN-G
Species:
UniProtKB ID:
Gene ID:
  • Human(288) Summary: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(11735) ankyrin 3, epithelial
  • Rat(361833) ankyrin 3, node of Ranvier (ankyrin G)
  • chicken(396309) ankyrin 3, node of Ranvier (ankyrin G)
  • cow(511203) ankyrin 3, node of Ranvier (ankyrin G)
  • Horse(100062775) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic cat(101097842) ankyrin 3, node of Ranvier (ankyrin G)
  • dog(479215) ankyrin 3, node of Ranvier (ankyrin G)
  • naked mole-rat(101719656) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic guinea pig(100734552) ankyrin 3, node of Ranvier (ankyrin G)
  • sheep(101120296) ankyrin 3, node of Ranvier (ankyrin G)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Ankyrin-G Antibody, clone N106/36, clone N106/36, from mouse,
Species Reactivity
rat
Application
immunohistochemistry
Monoclonal Anti-Ankyrin G - Biotin antibody produced in mouse, clone S106-20, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-Ankyrin G - Fitc antibody produced in mouse, clone S106-20, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-Ankyrin G - Apc antibody produced in mouse, clone S106-20, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-Ankyrin G - Percp antibody produced in mouse, clone S106-20, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ank3,
Species
mouse
MISSION® esiRNA, targeting human ANK3,
Species
human