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Merck

330678

Avanti

SM ELISA (Clear)

Avanti Research - A Croda Brand

Sinónimos:

SM ELISA, Brain Sphingomyelin ELISA Snoopers, Clear, for use in absorbance applications

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.84

Formulario

liquid

fabricante / nombre comercial

Avanti Research - A Croda Brand

envase

1 ea of 1 × (ELISA strip packaged in foil pouch)

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

Descripción general

Avanti Lipid Snoopers are lipid microarrays useful in semi-quantitative measurements. These snoopers are relatively stable and provide a higher sensitivity compared to the conventional enzyme-linked immunosorbent assay (ELISA) methods. Sphingomyelin (SM) is a sphingolipid present in central nervous system as a component of the myelin sheath and neuronal cells. It is synthesized from ceramide in Golgi. Acid sphingomyelinase (aSMase) degrades SM.
ELISA Snoopers are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
  • quantitative lipid-protein binding studies
  • assemble a 96-well plate using only the lipids of interest for binding studies
  • flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.


The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.

Acciones bioquímicas o fisiológicas

Sphingomyelin (SM) participates in the inflammatory process and signalling pathways. It is a crucial regulator for myelin integrity, axon maturation, cognition and brain development. The SM to ceramide ratio is crucial, as high ceremide levels are implicated in depression. Altered levels of sphingomyelin due to sphingomyelinase deficiency results in Niemann–Pick disease.

Envase

ELISA Strip Packaged in Foil Pouch (330678-1EA)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

No data available

Punto de inflamabilidad (°C)

No data available


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Sphingolipid metabolism in neural cells
van ED, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1758(12), 1978-1994 (2006)
Sphingolipids: membrane microdomains in brain development, function and neurological diseases
Olsen ASB and Faergeman NJ
Open Biology, 7(5), 170069-170069 (2017)
Sphingomyelin in brain and cognitive development: preliminary data
Schneider N, et al.
eNeuro (2019)
Avanti lipid tools: connecting lipids, technology, and cell biology
Sims KH, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)

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