SML3797

Biotin-HPDP

≥95% (HPLC)

• Synonym(e): (3aS,4S,6aR)-Hexahydro-2-oxo-N-[6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]-1H-thieno[3,4-d]imidazole-4-pentanamide, HPDP-Biotin, N-[6-(Biotinamido)hexyl]-3′-(2′-pyridyldithio)propionamide
• Empirische Formel (Hill-System): C₂₄H₃₇N₅O₃S₃
• CAS-Nummer: 129179-83-5
• Molekulargewicht: 539.78
• MDL-Nummer: MFCD00078541
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Lagerbedingungen: protect from light
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear (Warmed)
• Lagertemp.: -10 to -25°C

Beschreibung

Biochem./physiol. Wirkung

Biotin-HPDP (HPDP-Biotin) is a membrane-permeable and reversible biotinylating reagent that is used to biotinylate target proteins via covalent disulfide bond (-S-S-) formation with free sulfhydryl (-SH) groups. The biotin-tagged proteins can then be subjected to affinity labeling or isolation/purification using avidin conjugates or beads. Unlike tranditonal biotinylation methods, Biotin-HPDP tag can be removed with reducing agents such as dithiothreitol (DTT) without the need of harsh reagents to dissociate the high affinity interaction between avidin and biotin.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable