L8000

L-Leucin

≥98% (HPLC), suitable for ligand binding assays

• Synonym(e): (S)-2-Amino-4-methylpentansäure
• Lineare Formel: (CH₃)₂CHCH₂CH(NH₂)CO₂H
• CAS-Nummer: 61-90-5
• Molekulargewicht: 131.17
• Beilstein: 1721722
• EG-Nummer: 200-522-0
• MDL-Nummer: MFCD00002617
• UNSPSC-Code: 12352209
• eCl@ss: 32160406
• PubChem Substanz-ID: 24896488
• NACRES: NA.26

Eigenschaften

• product name: L-Leucin, reagent grade, ≥98% (HPLC)
• Qualität: reagent grade
• Qualitätsniveau: 200
• Assay: ≥98% (HPLC)
• Form: powder
• Methode(n): ligand binding assay: suitable
• Verunreinigungen: isoleucine and methionine, essentially free
• Farbe: white to off-white
• mp (Schmelzpunkt): >300 °C (lit.)
• Anwendung(en): peptide synthesis
• SMILES String: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
• InChIKey: ROHFNLRQFUQHCH-YFKPBYRVSA-N

Beschreibung

Anwendung

L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.

Biochem./physiol. Wirkung

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)