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K2126

Sigma-Aldrich

β-Estradiol-6-one 6-(O-Carboxymethyloxim)

≥98.00% (TLC), powder

Synonym(e):

β-Oestradiol-6-(O-carboxymethyl)-oxim, 1,3,5(10)-Oestratriene-3,17β-diol-6-on-6-(O-carboxymethyloxim), 3,17β-Dihydroxy-1,3,5(10)-oestratrien-6-(O-carboxymethyl)-oxim, 6-Keto-oestradiol-6-(O-carboxymethyloxim)

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About This Item

Empirische Formel (Hill-System):
C20H25NO5
CAS-Nummer:
35048-47-6
Molekulargewicht:
359.42
Beilstein:
2484202
MDL-Nummer:
MFCD00056459
UNSPSC-Code:
51111800
PubChem Substanz-ID:
329817132
NACRES:
NA.77

product name

β-Estradiol-6-one 6-(O-Carboxymethyloxim),

Biologische Quelle

synthetic (organic)

Qualitätsniveau

200

Assay

≥98.00% (TLC)

Form

powder

Löslichkeit

ethanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

Versandbedingung

ambient

Lagertemp.

2-8°C

SMILES String

C[C@]12CC[C@H]3[C@@H](C\C(=N\OCC(O)=O)c4cc(O)ccc34)[C@@H]1CC[C@@H]2O

InChI

1S/C20H25NO5/c1-20-7-6-13-12-3-2-11(22)8-15(12)17(21-26-10-19(24)25)9-14(13)16(20)4-5-18(20)23/h2-3,8,13-14,16,18,22-23H,4-7,9-10H2,1H3,(H,24,25)/b21-17-/t13-,14-,16+,18+,20+/m1/s1

InChIKey

AWARIMYXKAIIGO-UYGYUSPXSA-N

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Allgemeine Beschreibung

β-Estradiol-6-one 6-(O-carboxymethyloxime) is a derivative of 17β-estradiol.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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C M Furnival et al.
The British journal of surgery, 70(8), 457-459 (1983-08-01)
The performance of a fluorescent cytochemical oestrogen receptor (ER) assay has been compared with an established dextran-coated charcoal ER assay in 85 cases of primary breast cancer. Both assays were performed on tissue samples from the same tumour, by independent
H Zheng et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 26(5), 336-340 (1991-01-01)
Estradiol conjugate has been used as a tracer to detect estrogen receptor of human mammary cancer cells. In order to look for more stable carrier of fluorescent estradiol conjugate, we substituted polyethyleneglycol (PEG) for bovine serum albumin (BSA) and synthsized
M Hill et al.
Journal of chromatography. B, Biomedical sciences and applications, 691(1), 187-191 (1997-03-28)
The conventional methods for characterization of steroid immunogens are based on the determination of the total amount of hapten bound to the protein carrier either by the UV spectroscopy or titration of unsubstituted amino groups. These methods do not allow
Mingzhe Liu et al.
Journal of bioscience and bioengineering, 111(5), 564-568 (2011-02-01)
Antibodies were covalently conjugated with poly(ethylene glycol) (PEG) and the properties of the PEGylated antibodies in organic media were investigated. Two types of monoclonal antibody were used in this study. One was a monoclonal antibody (abzyme) that was prepared against
May L Chiu et al.
Biotechnology and applied biochemistry, 58(1), 75-82 (2011-03-31)
A convenient homogeneous enzyme immunoassay for estradiol is described. Unlike heterogeneous immunoassays, which require time-consuming separation steps or expensive automated systems, homogeneous immunoassays, wherein all reagents are freely suspended in bulk solution, can be simple and fast without costly instrumentation.
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