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C5020

Sigma-Aldrich

Cefazolin Natriumsalz

89.1-110.1%

Synonym(e):

Cefazoline sodium, Monosodium cefazolin

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About This Item

Empirische Formel (Hill-System):
C14H13N8NaO4S3
CAS-Nummer:
27164-46-1
Molekulargewicht:
476.49
Beilstein:
3585038
EG-Nummer:
248-278-4
MDL-Nummer:
MFCD00056883
UNSPSC-Code:
51282532
PubChem Substanz-ID:
24278318
NACRES:
NA.76

Qualitätsniveau

200

Assay

89.1-110.1%

Form

powder

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria

Wirkungsweise

cell wall synthesis | interferes

Lagertemp.

2-8°C

SMILES String

[Na+].Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C([O-])=O)s1

InChI

1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/q;+1/p-1/t9-,12-;/m1./s1

InChIKey

FLKYBGKDCCEQQM-WYUVZMMLSA-M

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Verwandte Kategorien

Allgemeine Beschreibung

Chemical structure: ß-lactam

Biochem./physiol. Wirkung

Used to study the effect of expression, binding and inhibition of penicillin-binding proteins, especially PBP2 and PBP4 on bacterial cell wall mucopeptide synthesis.

Angaben zur Herstellung

Freely soluble in water, very slightly soluble in chloroform and ethanol.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H317,H334

Gefahreneinstufungen

Resp. Sens. 1 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Journal of biomedical materials research. Part B, Applied biomaterials, 106(2), 751-759 (2017-03-24)
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Journal of peptide science : an official publication of the European Peptide Society, 23(10), 777-789 (2017-07-15)
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Pharmacokinetic studies and therapeutic drug monitoring of antibiotics require a simple, rapid, and reliable analytical method for monitoring the concentrations in plasma, including unbound concentrations for highly protein-bound drugs. The aim of the current work was to develop and validate
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