N4126

Nicotinsäure

≥98%

• Synonym(e): 3-Picolinsäure, Niacin, Pellagra Präventivfaktor, Pyridin-3-carbonsäure, Vitamin B₃
• Empirische Formel (Hill-System): C₆H₅NO₂
• CAS-Nummer: 59-67-6
• Molekulargewicht: 123.11
• Beilstein: 109591
• EG-Nummer: 200-441-0
• MDL-Nummer: MFCD00006391
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 24897668
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Assay: ≥98%
• Form: powder
• Farbe: white to off-white
• mp (Schmelzpunkt): 236-239 °C (lit.)
• SMILES String: OC(=O)c1cccnc1
• InChI: 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
• InChIKey: PVNIIMVLHYAWGP-UHFFFAOYSA-N
• Angaben zum Gen: human ... CYP1A2(1544) ; rat ... Chrnb2(54239)

Beschreibung

Allgemeine Beschreibung

Nicotinic acid is also known as vitamin B₃ or Niacin. It is a water soluble vitamin. Niacin can be either synthesized within the body or can be obtained from dietary sources.

Anwendung

Nicotinic acid has been used:

• as a component of the MS vitamins stock solution
• for the detection of siderophores in Escherichia coli bacterial culture
• as a component of the holidic medium for adult Drosophila .

Biochem./physiol. Wirkung

Niacin is involved in the production of nicotinamide adenine dinucleotide (NAD⁺), which is used in the adenine triphosphate (ATP) production in mitochondrial oxidative phosphorylation. It also decreases hepatic production of very-low density lipoproteins (VLDL), and apolipoprotein B (apo-B). Niacin deficiency leads to pellagra.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319
• P-Sätze: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): 379.4 °F - closed cup
• Flammpunkt (°C): 193 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves