902284

TyrannoPhos

• Synonym(e): Cyclopentylbis(3,5-di-tert-butylphenyl)phosphine, Phosphine ligand for nickel catalysis
• Empirische Formel (Hill-System): C₃₃H₅₁P
• CAS-Nummer: 2097604-70-9
• Molekulargewicht: 478.73
• MDL-Nummer: MFCD32068357
• UNSPSC-Code: 12161600
• NACRES: NA.22

Eigenschaften

• Form: powder or crystals
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings; reagent type: ligand
• Funktionelle Gruppe: phosphine
• SMILES String: CC(C1=CC(P(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)C3CCCC3)=CC(C(C)(C)C)=C1)(C)C
• InChI: 1S/C33H51P/c1-30(2,3)23-17-24(31(4,5)6)20-28(19-23)34(27-15-13-14-16-27)29-21-25(32(7,8)9)18-26(22-29)33(10,11)12/h17-22,27H,13-16H2,1-12H3
• InChIKey: IWPJBOKLLTVJMY-UHFFFAOYSA-N

Beschreibung

Anwendung

This new aryl alkylphosphine ligand developed in Abby′s Doyle′s lab has been tailored specifically for nickel catalysis as demonstrated in the Suzuki coupling of acetals with boronic acids to generate benzylic ethers, reactions that pose challenges in Ni catalysis when using phosphine ligands developed for Pd-catalysed couplings.

Sonstige Hinweise

Parameterization of phosphine ligands demonstrates enhacement of nickel catalysis via remote steric effects

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable