638439

(2-Biphenylyl)-di-tert.-butylphosphin

97%

• Synonym(e): (2-Biphenyl)-di-tert.-butylphosphin, 2-(Di-tert.-butylphosphino)-biphenyl, JohnPhos
• Lineare Formel: C₆H₅C₆H₄P[C(CH₃)₃]₂
• CAS-Nummer: 224311-51-7
• Molekulargewicht: 298.40
• Beilstein: 8322131
• MDL-Nummer: MFCD01862440
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24882938
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Eignung der Reaktion: reaction type: Cross Couplings; reagent type: ligand; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reagent type: ligand; reaction type: C-X Bond Formation; reagent type: ligand; reaction type: Heck Reaction; reagent type: ligand; reaction type: Suzuki-Miyaura Coupling
• mp (Schmelzpunkt): 86-88 °C (lit.)
• Funktionelle Gruppe: phosphine
• SMILES String: CC(C)(C)P(c1ccccc1-c2ccccc2)C(C)(C)C
• InChI: 1S/C20H27P/c1-19(2,3)21(20(4,5)6)18-15-11-10-14-17(18)16-12-8-7-9-13-16/h7-15H,1-6H3
• InChIKey: CNXMDTWQWLGCPE-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

JohnPhos is a Buchwald′s sterically bulky biaryl phosphine ligand. It is a reactive dialkylbiaryl phosphine ligand which catalyzes the carbon-nitrogen bond-forming reactions. Coordination chemistry of gold catalysts bearing JohnPhos as ligand has been investigated by NMR spectroscopy.

Learn more about Buchwald Phosphine Ligands

Anwendung

Bulky biarylphosphine ligand utilized in the palladium catalyzed Stille cross-coupling reaction.

Bulky phosphine ligand used in a Pd-catalyzed 2,3-diarylation of α,α-disubstituted-3-thiophenemethanols via cleavage of C-H and C-C bonds.

Ligand utilized in amination of aryl halides and aryl triflates.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)