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A9563

Sigma-Aldrich

4-Aminophenylmercursäureacetat

≥90% (titration)

Synonym(e):

4-(Acetoxymercuri)-anilin, APMA

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About This Item

Lineare Formel:
CH3CO2HgC6H4NH2
CAS-Nummer:
6283-24-5
Molekulargewicht:
351.75
Beilstein:
3664749
EG-Nummer:
228-497-1
MDL-Nummer:
MFCD00007820
UNSPSC-Code:
12352103
PubChem Substanz-ID:
57653899
NACRES:
NA.22

Assay

≥90% (titration)

Form

powder

mp (Schmelzpunkt)

163-165 °C (lit.)

Löslichkeit

DMSO: soluble 10 mg/mL
H2O: soluble 5 mM
glacial acetic acid: soluble 50 mg/mL

SMILES String

CC(=O)O[Hg]c1ccc(N)cc1

InChI

1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1

InChIKey

RXSUFCOOZSGWSW-UHFFFAOYSA-M

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Biochem./physiol. Wirkung

An organomercurial activator of matrix metalloproteinases.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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A Bianchi et al.
Osteoarthritis and cartilage, 24(11), 1961-1969 (2016-10-21)
Fibroblast Growth Factor 23 (FGF23) may represent an attractive candidate that could participate to the osteoarthritic (OA)-induced phenotype switch of chondrocytes. To address this hypothesis, we investigated the expression of FGF23, its receptors (FGFRs) and co-receptor (Klotho) in human cartilage
Manuel Johanns et al.
Scientific reports, 7(1), 4328-4328 (2017-07-01)
Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance. We previously showed that low-density lipoprotein receptor-related protein-1 (LRP-1) mediates the clearance of a complex between the zymogen form of MMP-2 (proMMP-2) and tissue
K R French et al.
Equine veterinary journal, 36(3), 261-266 (2004-05-19)
Acute laminitis is characterised by hoof lamellar dermal-epidermal separation at the basement membrane (BM) zone. Hoof lamellar explants cultured in vitro can also be made to separate at the basement membrane zone and investigating how this occurs may give insight
Nian-Qiu Shi et al.
International journal of nanomedicine, 7, 1613-1621 (2012-05-24)
The use of activable cell-penetrating peptides (ACPPs) as molecular imaging probes is a promising new approach for the visualization of enzymes. The cell-penetrating function of a polycationic cell-penetrating peptide (CPP) is efficiently blocked by intramolecular electrostatic interactions with a polyanionic
Jan-Olof Winberg et al.
European journal of biochemistry, 270(19), 3996-4007 (2003-09-27)
In the leukemic macrophage cell-line THP-1, a fraction of the secreted matrix metalloproteinase 9 (MMP-9) is linked to the core protein of chondroitin sulfate proteoglycans (CSPG). Unlike the monomeric and homodimeric forms of MMP-9, the addition of exogenous CaCl2 to
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