Alle Fotos(3)

Dokumente

L9756

(−)-Tetramisol -hydrochlorid

Name: (−)-Tetramisol -hydrochlorid
Brand: SIGMA

powder, ≥99% (GC)

Synonym(e):

(S)-(−)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazol -hydrochlorid, L(−)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazol -hydrochlorid, Levamisol -hydrochlorid

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(3)

About This Item

Empirische Formel (Hill-System):

C₁₁H₁₂N₂S · HCl

CAS-Nummer:

16595-80-5

Molekulargewicht:

240.75

Beilstein:

4358988

EG-Nummer:

240-654-6

MDL-Nummer:

MFCD00012675

UNSPSC-Code:

12352202

PubChem Substanz-ID:

24278526

NACRES:

NA.77

product name

(−)-Tetramisol -hydrochlorid, ≥99% (GC)

Biologische Quelle

synthetic (organic)

Assay

≥99% (GC)

Form

powder

mp (Schmelzpunkt)

228-230 °C

Löslichkeit

water: 50 mg/mL, clear, colorless to faintly yellow

Wirkungsspektrum von Antibiotika

parasites

Wirkungsweise

enzyme | inhibits

SMILES String

Cl.C1CN2C[C@@H](N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1

InChIKey

LAZPBGZRMVRFKY-HNCPQSOCSA-N

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Anwendung

Suitable for inhibition of various mammalian alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor).
Intestinal alkaline phosphatases are only slightly inhibited.
Not for veterinary use.

Biochem./physiol. Wirkung

Zeigt sowohl immunstimulierende als auch immunsuppressive Wirkungen, abhängig von verschiedenen steuerbaren Faktoren. Sehr wirksam bei der Behandlung von Ascariasis (Hakenwürmer Befall). Nützlich in der Chemotherapie von kolorektalen Karzinomen, möglicherweise aufgrund seiner Stimulation der IL-1 Produktion und direkter Aktivierung von Makrophagen.

Sonstige Hinweise

Levamisole hydrochloride is soluble in water at 50mg/mL yielding a clear, colorless solution. Solutions are stable at 2-8°C for ~1 month.

Piktogramme

GHS06

Signalwort

Danger

H-Sätze

H301

P-Sätze

P301 + P310 + P330

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 3

1 of 3

Sigma-Aldrich

901233

(2R)-2-Phenyl-3,4-dihydro-2H-pyrimido[2,1-b][1,3]benzothiazole

Roche

11442074001

BM Purple

Supelco

33386

Aldicarb

Quantification of Tyrosine Hydroxylase and ErbB4 in the Locus Coeruleus of Mood Disorder Patients Using a Multispectral Method to Prevent Interference with Immunocytochemical Signals by Neuromelanin.

Lei Guo et al.

Neuroscience bulletin, 35(2), 205-215 (2019-02-02)

The locus coeruleus (LC) has been studied in major depressive disorder (MDD) and bipolar disorder (BD). A major problem of immunocytochemical studies in the human LC is interference with the staining of the immunocytochemical end-product by the omnipresent natural brown

Entosis Controls a Developmental Cell Clearance in C. elegans.

Yongchan Lee et al.

Cell reports, 26(12), 3212-3220 (2019-03-21)

Metazoan cell death mechanisms are diverse and include numerous non-apoptotic programs. One program called entosis involves the invasion of live cells into their neighbors and is known to occur in cancers. Here, we identify a developmental function for entosis: to

Synthesis and evaluation of thiophenyl derivatives as inhibitors of alkaline phosphatase.

Lei Chang et al.

Bioorganic & medicinal chemistry letters, 21(8), 2297-2301 (2011-03-23)

Pathological calcifications induced by deposition of basic phosphate crystals or hydroxyapatite (HA) on soft tissues are a large family of diseases comprising of ankylosing spondylitis (AS), end-stage osteoarthritis (OA) and vascular calcification. High activity of tissue non-specific alkaline phosphatase (TNAP)

Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases.

Lina Li et al.

Bioorganic & medicinal chemistry, 17(20), 7290-7300 (2009-09-29)

Presence of basic calcium phosphate in knee joints of osteoarthritis patients could be prevented by inhibiting tissue non-specific alkaline phosphatase (TNAP) activity. Levamisole or the L stereoisomer of tetramisole (a known TNAP inhibitor) has been used as a treatment for

Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation.

Agnes Cheong et al.

Development (Cambridge, England), 147(10) (2020-05-08)

Mitochondria are essential for energy production and although they have their own genome, many nuclear-encoded mitochondrial ribosomal proteins (MRPs) are required for proper function of the organelle. Although mutations in MRPs have been associated with human diseases, little is known

Alle zugehörigen Dokumente anzeigen

Protokolle

Immunohistochemistry Procedure

Use this protocol to for the entire immunohistochemistry (IHC) procedure through staining and visualization of specific antigens in paraffin-embedded tissue sections.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.