906794

Bis(neopentyltrimethylammonium) oxalate

• Synonym(e): N,N,N,2,2-Pentamethylpropan-1-aminium oxalate, Bis(trimethylneopentylammonium) oxalate
• Empirische Formel (Hill-System): C₁₈H₄₀N₂O₄
• CAS-Nummer: 2247698-66-2
• Molekulargewicht: 348.52

Eigenschaften

• Form: powder, crystals or chunks
• Lagertemp.: −20°C

Beschreibung

Anwendung

This bis(neopentyltrimethylammonium) oxalate is used in the elution step of the Ritter lab′s new method for deoxyfluorination of phenols. First, an Fmoc-protected ruthenium tyrosine amino acid derivative ([CpRu(Fmoc-tyrosin)]CF₃CO₂, cat# 902314) is incorporated to a peptide. Later, bis(neopentyltrimethylammonium) oxalate and chloroimidazolium chloride (cat# 904848) facilitate the elution of [¹⁸F]fluoride. The final [¹⁸F]fluoride radiolabeled polypeptide is useful in positron emission tomography (PET) imaging for the study of various biological applications.

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Vorsicht

Bis(neopentyltrimethylammonium) oxalate is hygroscopic and should be stored in a closed vial or in a desiccator.

Sonstige Hinweise

Site-SpecificDeoxyfluorination of Small Peptides with [¹⁸F]Fluoride

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable