317500

(1S,2R)-(+)-Norephedrin

98%

• Synonym(e): (1S,2R)-2-Amino-1-phenyl-1-propanol, erythro-α-(1-Aminoethyl)-benzylalkohol, D-(+)-Norephedrin, Phenylpropanolamin
• Lineare Formel: C₆H₅CH(OH)CH(CH₃)NH₂
• CAS-Nummer: 37577-28-9
• Molekulargewicht: 151.21
• Beilstein: 2802896
• MDL-Nummer: MFCD00064411
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24859081
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• Form: solid
• Optische Aktivität: [α]20/D +40°, c = 7 in 1 M HCl
• mp (Schmelzpunkt): 51-54 °C (lit.)
• Funktionelle Gruppe: amine; hydroxyl; phenyl
• Lagertemp.: 2-8°C
• SMILES String: C[C@@H](N)[C@@H](O)c1ccccc1
• InChI: 1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1
• InChIKey: DLNKOYKMWOXYQA-VXNVDRBHSA-N

Beschreibung

Allgemeine Beschreibung

(1S,2R)-(+)-Norephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.

Anwendung

(1S,2R)-(+)-Norephedrine may be used in the preparation of dendritic ligands, which on combining with Ru(II) complexes form efficient asymmetric transfer hydrogenation catalysts. It may also be used in the preparation of N-((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)furan-2-carboxamide. This chiral amide can efficiently catalyze the enantioselective ethylation of aromatic and heteroaromatic aldehydes to secondary alcohols in the absence of titanium tetraisopropoxide as promotor.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves