287636

(1S,2S)-(+)-Pseudoephedrin

98%

• Synonym(e): (+)-Pseudoephedrin, (+)-ψ-Ephedrin, (1S,2S)-2-Methylamino-1-phenyl-propanol, d-Isoephedrin, d-Pseudoephedrin
• Empirische Formel (Hill-System): C₁₀H₁₅NO
• CAS-Nummer: 90-82-4
• Molekulargewicht: 165.23
• Beilstein: 2414132
• EG-Nummer: 202-018-6
• MDL-Nummer: MFCD00064256
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24857282
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: solid
• Optische Aktivität: [α]20/D +52°, c = 0.6 in ethanol
• mp (Schmelzpunkt): 118-120 °C
• SMILES String: CN[C@@H](C)[C@@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m0/s1
• InChIKey: KWGRBVOPPLSCSI-WCBMZHEXSA-N

Beschreibung

Allgemeine Beschreibung

(1S,2S)-(+)-Pseudoephedrine, a natural enantiomer of ephedrine, is a decongestant commonly used in cold and allergy medicines.

Anwendung

(1S,2S)-(+)-Pseudoephedrine condenses with N,N-diisopropyl-2-formyl-1-naphthamide to form the corresponding oxazolidine derivative as a single diasterisomer.

(1S,2S)-(+)-Pseudoephedrine may be used as a chiral auxillary in asymmetric synthesis of enantioenriched organic compounds. It may also be used to prepare a novel tertiary pseudo C2-symmetric 1,2-diamine, which facilitates the enantioselective addition of methyl lithium to imines with better yield.

Biochem./physiol. Wirkung

Nicht-selektiver adrenergischer Agonist; abschwellend

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332,H315,H319,H335
• P-Sätze: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves