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Merck

HDAC1

histone deacetylase 1

Synonyme:
GON-10, HD1, RPD3, RPD3L1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3065) Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(433759) histone deacetylase 1
  • Rat(297893) histone deacetylase 1
  • Zebrafish(192302) histone deacetylase 1
  • chicken(373961) histone deacetylase 1
  • dog(487309) histone deacetylase 1
  • domestic cat(101099228) histone deacetylase 1
  • cow(404126) histone deacetylase 1
  • domestic guinea pig(100728529) histone deacetylase 1
  • naked mole-rat(101715102) histone deacetylase 1
  • sheep(100820752) histone deacetylase 1

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Activity Assay

Product Number
Beschreibung
Spezies
Histone Deacetylase Assay Kit, Fluorometric, sufficient for 100 assays (96 well plates),
Spezies
human

Small Molecule - Antagonist

Product Number
Beschreibung
Spezies
Buttersäure, ≥99%,
Spezies
human
Buttersäure, natural, ≥99%, FCC, FG,
Spezies
human
Buttersäure, ≥99%, FG,
Spezies
human
2-Propylpentansäure, ,
Spezies
rat, human, mouse

Antibodies

Product Number
Beschreibung
Speziesreaktivität
Anwendung
Anti-HDAC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-HDAC1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0510, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-HDAC1 antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
bovine, dog, guinea pig, human, mouse, rat
Anwendung
western blot
Anti-HDAC1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-HDAC1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Beschreibung
Spezies
SAHA, ≥98% (HPLC),
Spezies
human
2-Propylpentansäure, ,
Spezies
rat, human, mouse
Trichostatin A, ≥98% (HPLC), from Streptomyces sp.,
Spezies
human, mouse, rat
Romidepsin, ≥98% (HPLC),
Spezies
human
CI−994, ≥98% (HPLC), powder,
Spezies
human

Proteins

Product Number
Beschreibung
Spezies
HDAC-1 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
Spezies
human
HDAC 1 from Plasmodium falciparum, recombinant, expressed in baculovirus infected insect cells, ≥40% (SDS-PAGE),
Spezies
HDAC1, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Product Number
Beschreibung
Spezies
MISSION® esiRNA, targeting human HDAC1,
Spezies
human