1670207

Tolcapone

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 3,4-Dihydroxy-4′-methyl-5-nitrobenzophenone, Ro 40-7592
• Formula empirica (notazione di Hill): C₁₄H₁₁NO₅
• Numero CAS: 134308-13-7
• Peso molecolare: 273.24
• Numero MDL: MFCD00866569
• Codice UNSPSC: 41116107
• ID PubChem: 329751344
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: tolcapone
• Produttore/marchio commerciale: USP
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)[N+]([O-])=O
• InChI: 1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3; MIQPIUSUKVNLNT-UHFFFAOYSA-N
• Informazioni sul gene: human ... COMT(1312)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Tolcapone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Tolcapone Tablets

Azioni biochim/fisiol

Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS09
• Avvertenze: Warning
• Indicazioni di pericolo: H400
• Consigli di prudenza: P273 - P391 - P501
• Classi di pericolo: Aquatic Acute 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable