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Documenti fondamentali

1437450

USP

Methyl salicylate

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Oil of wintergreen, Wintergreen oil

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About This Item

Formula condensata:
2-(HO)C6H4CO2CH3
Numero CAS:
Peso molecolare:
152.15
Beilstein:
971516
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

pharmaceutical primary standard

Densità del vapore

5.26 (vs air)

Tensione di vapore

1 mmHg ( 54 °C)

Famiglia di API

methyl salicylate

Temp. autoaccensione

847 °F

Produttore/marchio commerciale

USP

Indice di rifrazione

n20/D 1.536 (lit.)

P. ebollizione

222 °C (lit.)

Punto di fusione

−8-−7 °C (lit.)

Densità

1.174 g/mL at 25 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

COC(=O)c1ccccc1O

InChI

1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3
OSWPMRLSEDHDFF-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Methyl salicylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

204.8 °F - closed cup

Punto d’infiammabilità (°C)

96 °C - closed cup


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Certificati d'analisi (COA)

Lot/Batch Number

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Sigma-Aldrich

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T Y Chan
Human & experimental toxicology, 15(9), 747-750 (1996-09-01)
Methyl salicylate (oil of wintergreen) is widely available in many over-the-counter liniments, ointments, lotions or medicated oils for the relief of musculoskeletal aches and pains. Ingestion of methyl salicylate poses the threat of severe, rapid-onset salicylate poisoning because of its
A Lapczynski et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45 Suppl 1, S428-S452 (2007-11-23)
A toxicologic and dermatologic review of methyl salicylate when used as a fragrance ingredient is presented.
Jonathan E Davis
The Journal of emergency medicine, 32(1), 63-69 (2007-01-24)
Serious toxicity can result from exposure to small amounts of methyl salicylate. Methyl salicylate is widely available as a component in many over-the-counter brands of creams, ointments, lotions, liniments and medicated oils intended for topical application to relieve musculoskeletal aches
Taraka R Donti et al.
Disease models & mechanisms, 7(2), 271-280 (2013-11-26)
Mutations in subunits of succinyl-CoA synthetase/ligase (SCS), a component of the citric acid cycle, are associated with mitochondrial encephalomyopathy, elevation of methylmalonic acid (MMA), and mitochondrial DNA (mtDNA) depletion. A FACS-based retroviral-mediated gene trap mutagenesis screen in mouse embryonic stem
Wen-Po Chuang et al.
The New phytologist, 201(3), 928-939 (2013-12-07)
Some plant-derived anti-herbivore defensive proteins are induced by insect feeding, resist digestion in the caterpillar gut and are eliminated in the frass. We have identified several maize proteins in fall armyworm (Spodoptera frugiperda) frass that potentially play a role in

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