1370462

Losartan Potassium

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol
• Formula empirica (notazione di Hill): C₂₂H₂₂ClKN₆O
• Numero CAS: 124750-99-8
• Peso molecolare: 461.00
• Beilstein: 5845770
• Numero MDL: MFCD02092704
• Codice UNSPSC: 41116107
• ID PubChem: 329750264
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: losartan
• Produttore/marchio commerciale: USP
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
• InChI: 1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1; OXCMYAYHXIHQOA-UHFFFAOYSA-N
• Informazioni sul gene: human ... AGTR1(185)

Descrizione

Descrizione generale

Losartan potassium is a new drug used for hypertension. It is nonpeptide angiotensin II (AII) receptor antagonist.

Losartan potassium is nonpeptide angiotensin II (AII) receptor antagonist and is orally active. It belongs to a new class of drugs introduced for clinical trials to treat hypertension.

Applicazioni

Losartan potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Losartan Potassium and Hydrochlorothiazide Tablets
• Losartan Potassium Tablets

Azioni biochim/fisiol

Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable