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504270

Supelco

Provetta Supelclean LC-18 SPE

bed wt. 100 mg, volume 1 mL, pk of 108

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About This Item

Codice UNSPSC:
41115712

Materiali

PE frit (20 μm porosity)
polypropylene hardware

Livello qualitativo

Nome Commerciale

Supelclean

Caratteristiche

endcapped

Composizione

bed wt., 100 mg

Confezionamento

pk of 108

Grado di funzionalizzazione

~11.5% C loading

tecniche

solid phase extraction (SPE): suitable

Area superficiale

475 m2/g

Volume

1 mL

Matrice

silica gel base material (irregularly shaped)

Gruppo funzionale matrice

C18 (octadecyl) bonding, monomerically bonded

Dimensione particelle

45 μm

Dimensione pori

0.8 cm3/g pore volume
60 Å pore size

applicazioni

food and beverages

Tecnica di separazione

reversed phase

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Descrizione generale

Supelclean LC-18 SPE tube is used in solid phase extraction (SPE) method to extract non-polar to moderately polar compounds from aqueous samples.

Applicazioni

Supelclean LC-18 SPE Tube may be used for the solid-phase extraction of:
  • Artesunate, dihydroartemisinin, mefloquine, amodiaquine and desethylamodiaquine in human plasma samples prior to their determination by reversed phase high performance liquid chromatography (RP-HPLC) coupled to electrochemical (EC) detector or ultraviolet (UV) detector.
  • Ursodeoxycholic acid in blood serum samples prior to its analysis by HPLC-UV.
  • Calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma samples after oral administration of Danggui Buxue Tang extract, prior to their pharmacokinetic studies by LC coupled to mass spectrometry (MS).

Note legali

Supelclean is a trademark of Sigma-Aldrich Co. LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination.
Lai CS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(5-6), 558-562 (2009)
Simultaneous determination of calycosin-7-O-β-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry.
Wen XD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 865(1-2), 99-105 (2008)
An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological studies of the drug combination.
Lai CS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 857(2), 308-314 (2007)
Barbara Sivakova et al.
International journal of molecular sciences, 22(4) (2021-02-13)
The phosphorylation of proteins modulates various functions of proteins and plays an important role in the regulation of cell signaling. In recent years, label-free quantitative (LFQ) phosphoproteomics has become a powerful tool to analyze the phosphorylation of proteins within complex
M Nobilis et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 937-946 (2001-03-15)
Ursodeoxycholic acid (3 alpha,7 beta-dihydroxy-5 beta-cholanoic acid, UDCA) is a therapeutically applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the treatment of chronic liver diseases associated with cholestasis. UDCA is more hydrophilic and less toxic

Articoli

Solid Phase Extraction: Reversed-Phase Methodology

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