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47773

Supelco

Phylloquinone (K1)

analytical standard

Sinonimo/i:

Vitamin K1, 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K1(20)

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About This Item

Formula empirica (notazione di Hill):
C31H46O2
Numero CAS:
84-80-0
Peso molecolare:
450.70
Beilstein:
2568816
Numero CE:
201-564-2
Numero MDL:
MFCD00214063
Codice UNSPSC:
12164500
ID PubChem:
24871410

Grado

analytical standard

Forma fisica

oil

CdA

current certificate can be downloaded

Caratteristiche

standard type fat soluble vitamin

Confezionamento

ampule of 100 mg

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Indice di rifrazione

n20/D 1.527 (lit.)

Punto di fusione

−20 °C (lit.)

Densità

0.984 g/mL at 25 °C (lit.)

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
MBWXNTAXLNYFJB-NKFFZRIASA-N

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Categorie correlate

Descrizione generale

Phylloquinone (K1) is a prenylated naphthoquinone. It is a fat soluble vitamin, produced by plants, green algae and some species of cyanobacteria. It functions as a coenzyme and is important for the synthesis of a number of proteins involved in blood clotting and bone metabolism.

Applicazioni

Phylloquinone (K1) may be used as an analytical reference standard for the quantification of the analyte in olive oil, chard, human plasma samples, animal and plant food products using reversed-phase high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
LRAD3004
LRAC9898
LRAC4249
LRAC0031
LRAB7993

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Phytomenadione European Pharmacopoeia (EP) Reference Standard

P1609000

Phytomenadione

Vitamin K1-4a,5,6,7,8,8a-13C6 ≥99 atom % 13C, ≥98% (CP)

Sigma-Aldrich

809888

Vitamin K1-4a,5,6,7,8,8a-13C6

Menadione (K3) analytical standard

Supelco

47775

Menadione (K3)

Vitamin K1 2,3-epoxide ≥98.0% (HPLC)

Sigma-Aldrich

19697

Vitamin K1 2,3-epoxide

(±)-α-tocoferolo analytical standard

Supelco

47783

(±)-α-tocoferolo

Pyridoxine Hydrochloride (B6) analytical standard

Supelco

47862

Pyridoxine Hydrochloride (B6)

Vitamin K2 (MK-4) solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

V-031

Vitamin K2 (MK-4) solution

Menaquinone-7 United States Pharmacopeia (USP) Reference Standard

USP

1381119

Menaquinone-7

Colecalciferolo (D3) analytical standard

Supelco

47763

Colecalciferolo (D3)

Determination of vitamin K1 content in olive oil, chard and human plasma by RP-HPLC method with UV?Vis detection
Otles S and Cagindi O
Food Chemistry, 100(3), 1220-1222 (2007)
Application of a simplified HPLC assay for the determination of phylloquinone (vitamin K1) in animal and plant food items
Jakob E and Elmadfa I
Food Chemistry, 56(1), 87-91 (1996)
Rogier Caluwé et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(7), 1385-1390 (2013-11-29)
Haemodialysis patients suffer from accelerated vascular calcification. The vitamin K-dependent matrix Gla protein (MGP) is one of the most powerful inhibitors of vascular calcification. Haemodialysis patients have high levels of the inactive form of MGP (desphosphorylated-uncarboxylated-MGP, dp-uc-MGP) and may benefit
Thilo Krüger et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(11), 2618-2624 (2013-08-31)
Vascular calcification is an independent risk factor for cardiovascular disease. Once thought to be a passive process, vascular calcification is now known to be actively prevented by proteins acting systemically (fetuin-A) or locally (matrix Gla protein). Warfarin is a vitamin
Joline W J Beulens et al.
The British journal of nutrition, 110(8), 1357-1368 (2013-04-18)
Recent reports have attributed the potential health benefits of vitamin K beyond its function to activate hepatic coagulation factors. Moreover, several studies have suggested that menaquinones, also known as vitamin K2, may be more effective in activating extra-hepatic vitamin K-dependent
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Protocolli

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

Separation of Retinyl acetate, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; δ-Tocopherol, analytical standard; Retinol palmitate, analytical standard

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

Separation of Retinyl acetate, analytical standard; δ-Tocopherol, analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Retinol palmitate, analytical standard.

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