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Key Documents

T8441

Sigma-Aldrich

L-Threonine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Sinonimo/i:

(2S,3R)-2-Amino-3-hydroxybutyric acid

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About This Item

Formula condensata:
CH3CH(OH)CH(NH2)CO2H
Numero CAS:
Peso molecolare:
119.12
Beilstein:
1721646
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

product name

L-Threonine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Origine biologica

non-animal source

agenzia

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Nome Commerciale

BioXtra

Saggio

99.0-101.0%

Forma fisica

powder

Qualità

meets EP, JP, USP testing specifications

tecniche

cell culture | mammalian: suitable

Impurezze

endotoxin, tested

Colore

white

Punto di fusione

256 °C (dec.) (lit.)

Solubilità

H2O: 1 g/10 mL, clear, colorless

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
AYFVYJQAPQTCCC-GBXIJSLDSA-N

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Descrizione generale

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.

Applicazioni

L-Threonine has been used for the following :
  • To study the effect of heat on homoserine kinase activity
  • In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells
  • As a substrate to determine the L-threonine dehydrogenase activity
  • To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine

Azioni biochim/fisiol

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Regulation of L-Threonine Dehydrogenase in Somatic Cell Reprogramming
Chuanchun Han
Stem Cells, 31(5) (2013)
Use of a Plackett-Burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells.
Gonzalez-Leal IJ
Biotechnol. Progress, 27(6), 1709-1717 (2011)
Genome-wide identification of tolerance mechanisms toward p-coumaric acid in Pseudomonas putida
Patricia Calero
Biotechnology and Bioengineering, 115(3), 762-774 (2018)
Homoserine Kinase from Escherichia coli K-12: Properties,
Inhibition by L-Threonine, and Regulation of Biosynthesis
J. THEZE
Journal of Bacteriology, 118(2), 577-581 (1974)
Systems metabolic engineering of Escherichia coli for L?threonine production.
Lee HK, et al.
Molecular Systems Biology, 3(1), 149-149 (2007)

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