SML3775

Desthiobiotin-Phenol

≥98% (HPLC)

• Sinonimo/i: (4R,5S)-N-[2-(4-Hydroxyphenyl)ethyl]-5-methyl-2-oxo-4-imidazolidinehexanamide, DBP, Desthiobiotin-Tyramide, N-(4-Hydroxyphenethyl)-6-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)hexanamide, d-Desthiobiotin-Phenol
• Formula empirica (notazione di Hill): C₁₈H₂₇N₃O₃
• Numero CAS: 2242902-55-0
• Peso molecolare: 333.43
• Codice UNSPSC: 12352200
• NACRES: NA.21

Proprietà

• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Stato: powder
• Colore: white to beige
• Solubilità: DMSO: 2 mg/mL, clear
• Temperatura di conservazione: -10 to -25°C

Descrizione

Azioni biochim/fisiol

A peroxidase-sensitive desthiobiotin-phenol (DBP) probe that offers more efficient recovery of DBP-labeled peptides from streptavidin beads and stronger mass spectrometry intensity of modified membrane proteins and achieves greater sensitivity for tyrosine residues detection. DBP shows a similar reactivity to the protein when it is converted to the phenoxyl radical state as biotin-phenol/biotin-tyramide (BP) in ascorbate peroxidase (APEX) proximity labeling. DBP exhibits reduced affinity to streptavidin and does not suffer from sulfur oxidation issue during the radical generation.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable