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SMB00313

Sigma-Aldrich

Gastrodin

≥98% (HPLC)

Sinonimo/i:

(2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-(4-hydroxymethyl-phenoxy)-tetrahydro-pyran-3,4,5-triol, 4-β-D-glucopyranosyloxybenzyl alcohol, 4-Hydroxybenzyl alcohol 4-O-β-D-glucoside

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About This Item

Formula empirica (notazione di Hill):
C13H18O7
Numero CAS:
62499-27-8
Peso molecolare:
286.28
Numero MDL:
MFCD00272169
Codice UNSPSC:
12352205
ID PubChem:
329824945
NACRES:
NA.25

Origine biologica

plant (Gastrodia elata Blume)

Saggio

≥98% (HPLC)

Forma fisica

powder

applicazioni

detection
metabolomics
vitamins, nutraceuticals, and natural products

Temperatura di conservazione

2-8°C

Stringa SMILE

O[C@@H]1[C@@H](CO)O[C@@H](OC2=CC=C(CO)C=C2)[C@H](O)[C@H]1O

InChI

1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
PUQSUZTXKPLAPR-UJPOAAIJSA-N

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Categorie correlate

Descrizione generale

Gastrodin, a phenolic glucoside, is the main active ingredient of the traditional Chinese medicinal compound Tianma. Gastrodin is an active component of Gastrodia elata Blume, a herb belonging to the Orchidaceae family.

Applicazioni

Gastrodin has been used as a control to estimate the gastrodin content in the leaves, roots and stems of Anoectochilus formosanus Hayata.

Azioni biochim/fisiol

Gastrodin can penetrate through the blood-brain barrier and has been suggested to have neuroprotective effects against hypoxia. It is also known to reduce the immunoreactivity of gamma-aminobutyric acid shunt enzymes in hippocampal tissues. Traditionally, gastrodin is also known to be effective in the treatment of headache, vertigo, dizziness and convulsive disorders. Along with anticonvulsant property, it also possesses antiepileptic, anxiolytic, anti-inflammatory and antiobesity action. Gastrodin is also helps in learning and memory stimulation.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Enhanced Agronomic Traits and Medicinal Constituents of Autotetraploids in Anoectochilus formosanus Hayata, a Top-Grade Medicinal Orchid
Chung HH, et al.
Molecules (Basel), 22(11), 1907-1907 (2017)
Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson?s disease model
Kumar H, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM, 2013 (2013)
Tianyuan Ye et al.
International journal of molecular sciences, 19(12) (2018-12-14)
Patients with diabetes mellitus (DM) suffer more risks from diabetic encephalopathy such as cognitive dysfunction and depressive-like behaviors. Numerous studies show that ER (endoplasmic reticulum) stress and inflammation play important roles in the development of diabetic encephalopathy. Gastrodin (Gas), one
Yu Xing et al.
The international journal of biochemistry & cell biology, 109, 8-16 (2019-01-27)
The in vivo protective role of gastrodin (GSTD) in myocardial infarction (MI) has been reported. However, the underlying mechanism remains unclear. Herein, we aimed to explore the effects of GSTD on hypoxia-injured H9c2 cells as well as the downstream microRNAs
Jinyuan Yan et al.
BMC neuroscience, 20(1), 31-31 (2019-06-19)
Recently, the use of traditional Chinese medicine (TCM) has become more generally accepted, including by the Food and Drug Administration. To expand the use of TCM worldwide, it is important to study the molecular mechanisms by which TCM and its
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