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Key Documents

SAB5200106

Sigma-Aldrich

Anti-SCNN1B antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Sinonimo/i:

Anti-ENaC Beta, Anti-Scnn1b

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous glycerol solution

PM

antigen predicted mol wt 87 kDa

Reattività contro le specie

mouse, human, rat

Concentrazione

1 mg/mL

tecniche

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

N° accesso NCBI

NP_036780

N° accesso UniProt

P51168

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

rat ... Scnn1b(24767)

Descrizione generale

Sodium channel epithelial 1 β subunit (SCNN1B) is expressed in the posterior cerebral artery of rats. It is one of the subunits of epithelial sodium channels. The gene ID of the protein is 24767.

Specificità

Detects ~87 kDa.

Immunogeno

AA617–638 of the rat sequence

Azioni biochim/fisiol

Sodium channel epithelial 1 β subunit (SCNN1B) is involved in sodium transport in the epithelium.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

PBS, 50% glycerol, and 0.09% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Chengbiao Zhang et al.
American journal of physiology. Renal physiology, 312(4), F682-F688 (2017-04-04)
Mice transgenic for genomic segments harboring PHAII (pseudohypoaldosteronism type II) mutant Wnk4 (with-No-Lysine kinase 4) (TgWnk4PHAII) have hyperkalemia which is currently believed to be the result of high activity of Na-Cl cotransporter (NCC). This leads to decreasing Na+ delivery to
Lijun Wang et al.
Journal of the American Society of Nephrology : JASN, 26(11), 2678-2690 (2015-04-08)
Kcnj10 encodes the inwardly rectifying K(+) channel Kir4.1 in the basolateral membrane of the distal convoluted tubule (DCT) and is activated by c-Src. However, the regulation and function of this K(+) channel are incompletely characterized. Here, patch-clamp experiments in Kcnj10-transfected
Eok-Cheon Kim et al.
Experimental physiology, 97(4), 544-555 (2011-11-18)
It has been suggested that mechanosensitive ion channels initiate myogenic responses in vessels; however, the molecular identity of the mechanosensitive ion channel complex is unknown. Although previous reports have suggested that epithelial Na(+) channel (ENaC) proteins are mechanotransducers in arteries
Md Shahrier Amin et al.
Hypertension (Dallas, Tex. : 1979), 54(4), 860-867 (2009-07-29)
To elucidate the role of epithelial sodium channels (ENaCs) and Na(+)-K(+)-ATPase in Na(+) transport by the choroid plexus, we studied ENaC expression and Na(+) transport in the choroid plexus. Lateral ventricle choroid plexuses were obtained from young male Wistar, Dahl

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