SAB4504299

Anti-phospho-Casein Kinase II α (pTyr²⁵⁵) antibody produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 45 kDa
• Reattività contro le specie: human, mouse, rat
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:10000; western blot: 1:500-1:1000
• N° accesso NCBI: P68400
• N° accesso UniProt: P68400
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr255)
• Informazioni sul gene: human ... CSNK2A1(1457)

Descrizione

Descrizione generale

Casein kinase II α(CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13. 2-p13. 3.

Immunogeno

The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255.

Immunogen Range: 221-270

Azioni biochim/fisiol

Casein kinase II α(CK2) regulates T-cell polarization by initiating the activation of dendritic cells. CK2 participates in the development of breast carcinoma. Mutations in CK2 results in neurodevelopmental abnormalities and dysmorphic features. This protein induces prosurvival and proinflammatory signaling pathways.

Caratteristiche e vantaggi

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Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable