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Merck
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Key Documents

SAB1103857

Sigma-Aldrich

Anti-MUSTN1 (6-20) antibody produced in rabbit

IgG fraction of antiserum

Sinonimo/i:

Anti-Musculoskeletal, embryonic nuclear protein 1, Anti-Mustang

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

IgG fraction of antiserum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen ~9 kDa

Reattività contro le specie

human

tecniche

western blot: 1:500-1:2,000

N° accesso UniProt

Q8IVN3

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... MUSTN1(389125)

Descrizione generale

MUSTN1 gene was initially discovered in fracture callus tissue. The gene codes for a small nuclear protein and is known to be widely expressed in skeletal muscle. MUSTN1 expression is observed during embryogenesis in the developing muscles and somites. Its maximum expression is observed from the third month of life. The gene is highly conserved among the vertebrates. The gene is known to contain a nuclear localization sequence, phosphorylation and myristoylation sites.
Musculoskeletal, embryonic nuclear protein 1 (MUSTN1) is encoded by the gene is mapped to human chromosome 3p21.1.

Immunogeno

synthetic peptide corresponding to amino acids 6-20of human MUSTN1

Azioni biochim/fisiol

MUSTN1 is involved in bone development and regeneration, as well as chondrogenesis. It is critical in the regulation of myogenic differentiation and myofusion as its knock-down inhibits the processes.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Robert P Gersch et al.
Bone, 45(2), 330-338 (2009-05-05)
Mustn1 encodes a small nuclear protein expressed specifically in the musculoskeletal system that was originally identified as a strongly up-regulated gene during bone regeneration, especially in fracture callus proliferating chondrocytes. Further experiments were undertaken to investigate its expression and role
Cheng Liu et al.
American journal of physiology. Cell physiology, 298(5), C1100-C1108 (2010-02-05)
Mustn1 (Mustang, musculoskeletal temporally activated novel gene) was originally identified in fracture callus tissue, but its greatest expression is detected in skeletal muscle. Thus, we conducted experiments to investigate the expression and function of Mustn1 during myogenesis. Temporally, quantitative real-time
Allelic expression analysis of the osteoarthritis susceptibility locus that maps to chromosome 3p21 reveals cis-acting eQTLs at GNL3 and SPCS1
Gee F, et al.
BMC Medical Genetics, 15(1), 53-53 (2014)

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