Passa al contenuto
Merck
Tutte le immagini(3)

Documenti fondamentali

SAB1100901

Sigma-Aldrich

Anti-ARPC4 (26-40) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Sinonimo/i:

Anti-ARC20, Anti-Actin related protein 2/3 complex, subunit 4, Anti-p20-Arc

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

IgG fraction of antiserum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen ~20 kDa

Reattività contro le specie

human

tecniche

indirect immunofluorescence: suitable
western blot: 1:500-1:2,000

N° accesso UniProt

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... ARPC4(10093)

Descrizione generale

Actin related protein 2/3 complex, subunit 4 (ARPC4) is mapped to human chromosome 3p25.3. It is part of the ARP2/3 complex which connects this complex to the mother filament.

Immunogeno

synthetic peptide corresponding to amino acids 26-40 of human ARPC4

Applicazioni

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Azioni biochim/fisiol

Actin related protein 2/3 complex, subunit 4 (ARPC4) in plants is crucial for action dynamics and cordinates the tip growth and movement. It is highly expressed in most of the pancreatic carcinoma and may regulate cancer cell migration. It interacts with mycobacterial protein Rv1626 and its expression in Mycobacterium tuberculosis impacts its survival and infection profile, making it an effective anti-tuberculosis drug candidate.

Stato fisico

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Expression of the ARPC4 subunit of human Arp2/3 severely affects Mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages
Ghosh A, et al.
Testing, 8(7), e69949-e69949 (2013)
The role of ARPC4 in tip growth and alignment of the polar axis in filaments of Physcomitrella patens
Perroud PF and Quatrano RS
Cell Motility and the Cytoskeleton, 63(3), 162-171 (2006)
Silencing of the ARP2/3 complex disturbs pancreatic cancer cell migration
Rauhala HE, et al.
Anticancer Research, 33(1), 45-52 (2013)
3p- syndrome defines a hearing loss locus in 3p25.3
McCullough BJ, et al.
Hearing Research, 224(1-2), 51-60 (2007)
Chiara Galloni et al.
The Journal of cell biology, 220(8) (2021-06-10)
The mechanisms regulating the disassembly of branched actin networks formed by the Arp2/3 complex still remain to be fully elucidated. In addition, the impact of Arp3 isoforms on the properties of Arp2/3 are also unexplored. We now demonstrate that Arp3

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.