S9381
Succinimide
99.1%
Sinonimo/i:
2,5-Pyrrolidinedione
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About This Item
Prodotti consigliati
Nome del prodotto
Succinimide,
Saggio
99.1%
Livello qualitativo
Stato
powder or crystals
Colore
white to off-white
P. ebollizione
285-290 °C (lit.)
Punto di fusione
123-125 °C (lit.)
Stringa SMILE
O=C1CCC(=O)N1
InChI
1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)
KZNICNPSHKQLFF-UHFFFAOYSA-N
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Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Journal of pharmaceutical and biomedical analysis, 72, 65-73 (2012-11-14)
Reversed-phase thin-layer chromatographic (RP TLC) retention coefficients for a newly designed series of N-phenyl-3-methyl succinimide derivatives, of a rationally expected anticonvusant activity, were determined as parameters of their lipophilicity. Basic pharmacokinetic descriptors of the agents were calculated in silico with
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The rapid racemization of aspartic acid (Asp) residues in peptides and proteins is due mainly to the succinimide intermediate. However, there should be another mechanism for Asp racemization without intermediacy of the succinimide. The direct H-atom abstraction from the C(alpha)-atom
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