S1940

Anti-phospho-Src (pTyr⁴¹⁸) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

• Sinonimo/i: Anti-pp60src(pY⁴¹⁸)
• Numero MDL: MFCD03455768
• Codice UNSPSC: 12352203
• NACRES: NA.44

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous glycerol solution
• Reattività contro le specie: chicken, mouse, human, rat
• tecniche: western blot: 1:1,000 using human platelets or mouse NIH3T3 cells
• N° accesso UniProt: P12931
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr418)
• Informazioni sul gene: human ... SRC(6714) ; mouse ... Src(20779) ; rat ... Src(83805)

Descrizione

Descrizione generale

Src is a proto-oncogene that regulates neuronal functions, such as nerve cell differentiation. The Src kinase family structurally comprises of SH2, SH3 and kinase domains, as well as a negative regulatory C-terminal tail. Src has also been implicated in functions such as cell growth, development and cell-cell interactions . Anti-phospho-Src p(Tyr⁴¹⁸) antibody is specific for human, mouse, rat and chicken Src (60 kDa).

Immunogeno

The sequence is conserved in human, mouse, chicken and frog.

synthetic phosphopeptide derived from the region of src that contains tyrosine 418, based on the sequence of human src.

Applicazioni

Anti-phospho-Src p(Tyr⁴¹⁸) antibody is suitable for use in western blot (1:1,000 using human platelets or mouse NIH3T3 cells). The product may also be used for immunoprecipitation (1:1000 using HEK293 or HEL cell lysates ).

Stato fisico

Solution in Dulbecco′s phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)