P3644

L-α-fosfatidilcolina

from soybean, Type IV-S, ≥30% (enzymatic)

• Sinonimo/i: 1,2-diacil-sn-glicero-3-fosfocolina, 3-sn-fosfatidilcolina, L-α-lecitina, Azolectina, PC
• Numero CAS: 8002-43-5
• Beilstein: 5209585
• Numero CE: 232-307-2
• Codice UNSPSC: 51321705
• NACRES: NA.25

Proprietà

• Origine biologica: soybean
• Livello qualitativo: 200
• Tipo: Type IV-S
• Forma fisica: solid
• Concentrazione: ≥30% (enzymatic)
• Solubilità: chloroform: soluble 100 mg/mL, clear to slightly hazy, yellow to orange
• Gruppo funzionale: phospholipid
• Tipo di lipide: phosphoglycerides
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1; JLPULHDHAOZNQI-ZTIMHPMXSA-N

Descrizione

Applicazioni

L-α-Phosphatidylcholine is suitable for use:

• as a component of human erythroid massive amplification culture (HEMA^def) medium for clinical expansion of human erythroblasts
• in the chloride efflux assay to examine the chloride permeability of lipid vesicles conferred by soluble CLIC1
• in an assay to measure solubilized wax synthase activity
• as a component of buffer A used for the resuspension of the cholate-solubilized catalytic unit of adenylate cyclase
• as a cryoprotectant for freezing ruminant sperm
• as a substrate for the estimation of phospholipase activity
• to make liposomes to assess their efficiency of recruitment of ARF (ADP ribosylation factor) and AP-1 (adaptor protein)
• in the preparation of the isolated catalytic unit of soluble adenylate cyclase

Azioni biochim/fisiol

Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells, forming the structural component of these membranes. It also serves as a reservoir for several lipid messengers and a source for several bioactive lipids such as, lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet activating factor, and arachidonic acid.

Una dei principali fosfolipidi strutturali del cervello, costituisce il 15% circa dei lipidi totali; localizzata soprattutto nella materia grigia.

Nota sulla preparazione

Purified from P 5638

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)