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Documenti fondamentali

P0643

Sigma-Aldrich

5-Propyl-2-thiouracil

≥98%

Sinonimo/i:

PTU

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About This Item

Formula empirica (notazione di Hill):
C7H10N2OS
Numero CAS:
Peso molecolare:
170.23
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51

Origine biologica

synthetic (organic)

Livello qualitativo

Saggio

≥98%

Stato

powder

Solubilità

1 M NH4OH: 50 mg/mL, clear to slightly hazy, colorless to light yellow

Stringa SMILE

CCCC1=CNC(=S)NC1=O

InChI

1S/C7H10N2OS/c1-2-3-5-4-8-7(11)9-6(5)10/h4H,2-3H2,1H3,(H2,8,9,10,11)
RWJRFPUNLXBCML-UHFFFAOYSA-N

Applicazioni

5-Propyl-2-thiouracil (PTU) is used to induce and study mechanisms of hypothyroidism at the levels of thyroid hormone biosynthesis and gene regulation.

Pittogrammi

Health hazard

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Carc. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Marion F Haug et al.
Frontiers in zoology, 7, 8-8 (2010-03-03)
Visual acuity, the ability of the visual system to distinguish two separate objects at a given angular distance, is influenced by the optical and neuronal properties of the visual system. Although many factors may contribute, the ultimate limit is photoreceptor
Ruby Bansal et al.
Endocrinology, 160(8), 1771-1785 (2019-05-29)
The CLARITY-BPA experiment, a large collaboration between the National Institute of Environmental Health Sciences, the National Toxicology Program, and the US Food and Drug Administration, is designed to test the effects of bisphenol A (BPA) on a variety of endocrine
Alessandra Gentili et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 33(12), 1793-1802 (2016-10-04)
This paper describes a rapid method for confirming residues of thyreostats in meat-based baby foods by using liquid chromatography - dual polarity electrospray - tandem mass spectrometry (LC-ES(±)-MS/MS). Six thioureylenes, belonging to the group of thiouracil and imidazole, were selected
Alexander G Little et al.
BMC biology, 11, 26-26 (2013-03-28)
Thyroid hormone (TH) is best known for its role in development in animals, and for its control of metabolic heat production (thermogenesis) during cold acclimation in mammals. It is unknown whether the regulatory role of TH in thermogenesis is derived
Lihua Liu et al.
Environmental pollution (Barking, Essex : 1987), 219, 1122-1130 (2016-09-13)
Short-chain chlorinated paraffins (SCCPs) are ubiquitous in the environment and might cause adverse environmental and human health effects. Little is known about the relative toxicity of different SCCP compounds especially during development. The objective of this study was to characterize

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